HiScreen™ columns prepacked with MabSelect™ resin are part of the process development platform available from Cytiva. The columns are an excellent choice for method optimization and parameter screening for capture of monoclonal antibodies (mAbs).
MabSelect™ resin is a BioProcess™ resin for capture of mAbs from large sample volumes.
Prepacked, ready-to-use columns for convenient process development.
10 cm bed height of HiScreen™ columns is designed to allow method optimization and parameter screening.
Easily connected in series to achieve 20 cm bed height.
Small bed volume gives fast results and minimal sample/buffer consumption.
Reproducible results, scalable to BioProcess™ columns packed with the same chromatography resin using the same linear fluid velocity.
The small column volume (4.7 mL) and bed height (10 cm) make HiScreen™ columns excellent tools for method optimization, parameter screening, robustness testing, and convenient scale-up. Process fluid velocities can be applied, because the 10 cm bed height gives enough residence time for the results to then serve as basis for linear process scale-up.
If necessary, two columns can easily be connected in series to give a bed height of 20 cm.
MabSelect™ resin is also available in other formats and as bulk packs, which makes it possible to use the same resins for development work, pilot studies, and routine production.
