Helenalin, NFkB inhibitor

Product Details

Formal Name: Natural sesquiterpenoid from Arnica species

Molecular Formula: C₁₅H₁₈O₄

Formula Weight: 262.31

CAS Number: 6754-13-8

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml).

Storage: -20°C

Stability: ≥ 2 years.

 

Applications

NFkB inhibitor

 

Functions

A novel sesquiterpene lactone which inhibits NFκB and displays potent anti-inflammatory activity. It suppresses essential immune functions of activated CD4+ T cells by multiple mechanisms. Also inhibits telomerase and this activity may be partially responsible for its anti-tumor effects.

 

Application Procedures

First dissolved in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

Research use only.

Documents

• Datasheet (PDF)
• MSDS (PDF)