Flupirtine maleate, K+ channel activator

Product Details

Formal Name: N-[2-Amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]carbamic acid ethyl ester maleate

Alternate Names: D9998

Molecular Formula: C₁₅H₁₇FN₄O₂ ∙ C₄H₄O₄

Formula Weight: 420.39

CAS Number: 75507-68-5

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 4 mg/ml).

Storage: RT

Stability: ≥ 2 years.

Applications

K+ channel activator

Functions

Activates KV7 potassium channels, indirectly antagonizes NMDA receptors and modulates GABAA receptors. Displays neuroprotective actions in a model of cerebral ischemia in mice and reduces apoptosis and necrosis induced by noxious stimuli. Analgesic activity. Active in vivo.

Application Procedures

First dissolved in DMSO (up to 40 mg/ml) or in Ethanol (up to 4 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Research use only.

Documents

• Datasheet (PDF)
• MSDS (PDF)