Solubility: Soluble in DMSO (up to 45 mg/ml) or in Water (up to 10 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Sodium channel blocker
Functions
Open Na+ channel blocker that inhibits fast Na+ current in cardiac muscle in a use- and concentration-dependent manner. Orally-active class Ic antiarrhythmic agent. Inhibits hERG potassium channels at clinically relevant concentrations.
Application Procedures
First dissolved in DMSO (up to 45 mg/ml) or in Water (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
