DMPQ 2HCl, PDGFRβ inhibitor

Product Details

Formal Name: 5,7-Dimethoxy-3-(4-pyridinyl)quinolone dihydrochloride

Molecular Formula: C₁₆H₁₄N₂O₂ · 2HCl

Formula Weight: 339.22

CAS Number: 1123491-15-5

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 1 mg/ml with warming) or in Water (up to 30 mg/ml).

Storage: RT

Stability: ≥ 2 years.

Applications

PDGFRβ inhibitor

Functions

A potent and selective inhibitor of PDGFRβ, IC50=80 nM. Greater than 100-fold more selective compared to EGFR, erb-B2, p56, PKA and PKC. Cell permeable.

Application Procedures

First dissolved in DMSO (up to 1 mg/ml with warming) or in Water (up to 30 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20° for up to 2 months.

Research use only.

Documents

• Datasheet (PDF)
• MSDS (PDF)