DMEM (Dulbecco’s Modification of Eagle’s Medium), high glucose

DMEM (Dulbecco’s Modified Eagle Medium) is one of the widely used basal mediums for supporting the growth of many different mammalian cells. DMEM is unique from other media as it contains 4 times the concentration of amino acids and vitamins than the original Eagle’s Minimal Essential Medium. Cells successfully cultured in DMEM include primary fibroblasts, neurons, glial cells, HUVECs, and smooth muscle cells, as well as cell lines such as HeLa, 293, Cos-7, and PC-12. We offer a variety of DMEM modifications for a range of cell culture applications.

The medium is modified with 4,500 mg/L glucose, L-glutamine, phenol red, sodium bicarbonate, and sodium pyruvate.

Related Products:

1. MSC Medium (TBS8021)
2. Chondrogenic Differentiation Medium (TBS8062)
3. RPMI16040 Medium (TBS8063)
4. ESC/iPSC-qualified FBS (TBS8002)
5. Adipocyte Differentiation Cocktail (TBS8017)

Research use only.

Documents

• Datasheet (PDF)
• MSDS (PDF)

References

1. Gu, T., Lu, A., Wang, X., Brahan, N., Xu, L., Zhang, L., Su, K., Seow, K., Vu, J., Luk, C., Lee, Y., Raman, A., Pazzi, J., & Njoo, E. (2024, October 14). Synthesis and evaluation of Carmofur analogs as antiproliferative agents, inhibitors to the main protease (mpro) of SARS-COV-2, and membrane rupture-inducing agents. bioRxiv. https://doi.org/10.1101/2024.10.11.617727

2. Gu, T., Raval, R., Bashkin, Z., Zhou, C., Ko, S., Kong, N., Hong, S., Bhaskara, A., Shah, S., Joshi, A., Thellakal, S., Rim, K., Marimuthu, A., Venkatesan, S., Wang, E., Li, S., Jayabalan, A., Tao, A., Fang, Y., … Njoo, E. (2025). Synthesis, antiproliferative activity, and biological profiling of C-19 trityl and silyl ether andrographolide analogs in colon cancer and breast cancer cells. Bioorganic & Medicinal Chemistry Letters, 130163. https://doi.org/10.1016/j.bmcl.2025.130163

3. Gutti, M., Luo, J., Sharma, V., Lee, E., Desarkar, A., Raval, R., Soedarmono, A., Zhu, J., & Njoo, E. (2025, January 14). Anticancer synthetic arylsulfonamides with WNT1-modulating activity. bioRxiv. https://doi.org/10.1101/2025.01.11.632297

4. Somani, S., Menta, L., Wang-Johanning, F., Johanning, G., Hong, S., & Njoo, E. (2025, April 03). Synthesis, anticancer properties, and biological profiling of synthetic glycan analogs of proscillaridin A. bioRxiv. https://doi.org/10.1101/2025.03.31.646140

5. Somani, S., Menta, L., Wang-Johanning, F., Johanning, G., Hong, S., & Njoo, E. (2025, October 27). Synthesis, anticancer properties, and biological profiling of synthetic glycan analogs of proscillaridin A. Discover Pharmaceutical Sciences. 1, 25 (2025). https://doi.org/10.1007/s44395-025-00025-1

6. Gutti, M., Tsui, M., Yang, S., Xi, S., Luo, J., Desarkar, A., Xie, Y., Feng, M., Avadhani, U., Raghavan, S., Brierley-Green, E., Yu, E., & Njoo, E. (2025). Synthetic Derivatives of Vinpocetine as Antiproliferative Agents. Drugs and Drug Candidates, 4(4), 53. https://doi.org/10.3390/ddc4040053

7. Lo, I., Vaidya, S., Mo, A., Chia, A. Y. X., Li, K., Parvin, J., … & Njoo, E. (2025). Blue Fluorescent Siloxytecans Exhibit Potent Anticancer Activity and Enable Direct Real-Time Quantification of Intracellular Uptake. ACS Bio & Med Chem Au. https://doi.org/10.1021/acsbiomedchemau.5c00155

Research use only.