Solubility: Soluble in DMSO (up to 5 mg/ml, with warming).
Storage: -20°C
Stability: ≥ 1 year.
Applications
Flavoprotein inhibitor
Functions
An irreversible inhibitor of iNOS and eNOS (IC50s=50 and 100 nM respectively. Binds to and inhibits the flavoprotein of neutrophil NADPH oxidase. Novel agonist for GPR3. Inhibits NFκB activation induced by IL-1β. Prevents early alcohol-induced liver injury in rodent models.
Application Procedures
First dissolved in DMSO (up to 5 mg/ml, with warming), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.
Research use only.
Specifications
Alternate names
DPI
Cas number
4673-26-1
Formulation
Powder
Formula weight
314.55
Molecular formula
C12H8I·Cl
Purity
>98%
Solubility
Soluble in DMSO (up to 5 mg/ml, with warming)
