Formal Name: Fermentation product produced by Metarrhizium anisopliae
Molecular Formula: C30H51N5O7
Formula Weight: 593.80
CAS Number: 2503-26-6
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 10 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Apoptosis inducer; anticancer agent
Functions
A cyclic depsipeptide produced by various species of fungi. Induces apoptosis in human nonsmall cell lung cancer cells. Displays selective cytotoxic effects on human oral cancer cell lines. Inhibits hepatocellular carcinoma cell growth via modulation of the Wnt/β-catenin pathway.
Application Procedures
First dissolved in DMSO (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
