Inhibits α-glucosidase I and II. Inhibits human immunodeficiency virus envelope glycoprotein-mediated membrane fusion at the CXCR4 binding step. May be used to produce an affinity ligand for purifying glucosidase 1. Was used to inhibit ER glucosidases I and II allowing for the discovery of a second mechanism for deglucosylation of N-linked oligosaccharides in PhaR1.7, a mouse lymphoma cell line.
Application Procedures
First dissolved in Water (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in distilled water may be stored at -20°C for up to 3 months.
