Microcarrier beads principally designed for use in suspension culture systems.
The macroporous structure of Cytopore microcarriers encourages cell growth into the bead, while the micropores provide maximum nutrient availability. The characteristics enable growth of cells which require high recirculation rates and high nutrient-availability.
Optimized for growth of r-CHO in stirred tank cultures but is applicable to cell lines requiring similar surface charge.
Transparent for easy microscopic examination of attached cells.
Macroporous Cytopore, microcarriers for cell culture
Cytopore1 macroporous microcarriers are principally designed for use in suspension culture systems for growth of adherent recombinant Chinese hamster ovary (r-CHO) cells, and the production of recombinant proteins.
Microcarrier culture is a technique which makes possible the high yield culture of anchorage-dependent cells. Cytopore microcarriers are macroporous making it possible for cells to grow in 3D. They supply an even larger surface area per volume to enhance this already high-yielding culture technique.
Features
The microcarriers are positively charged due to the DEAE groups coupled to the cellulose matrix.
The microcarriers have a very precise particle size distribution, and a network structure, where the ratio of surface area to particle material is more than 95 to 1.
The network structure enables stained cells to be closely observed while they grow inside the microcarriers.
