Cellbag™ bioreactor containers with Bioclear™ 10 film

Presterilized, single-use bioreactor bags for non-invasive animal cell cultivation, designed for use with ReadyToProcess WAVE™ Bioreactor systems.

• Cellbag™ bioreactor containers provide a robust environment for cell growth.
• These single-use bioreactors are suitable for process development, research, seed train, and cGMP manufacturing operations.
• Presterilized and disposable, ReadyToProcess WAVE™ bioreactor bags require no cleaning and minimize the risk of cross-contamination.
• Cellbag™ containers with Bioclear™ 10 provide mechanical strength for rocking bioreactor applications.

Overview of Cellbag™ bioreactor containers for cell culture

The Cellbag™ bioreactor container is mounted onto the electric rocking base unit of a WAVE™ Bioreactor system and inflated. Cell culture media and cells are loaded into the single-use chamber. The rocking motion of the base unit induces waves in the cell culture fluid to provide efficient mixing and gas transfer, which enables cell growth.

Variety of Cellbag™ bioreactor container options and configurations

The Cellbag™ bioreactor container portfolio offers volumes ranging from 0.5 to 200 L with many combinations of the following components:

• Air inlet filter
• Air outlet filter
• Needleless sampling port
• Inoculation/harvest lines
• Optical dissolved oxygen (DO) sensor
• Optical pH sensor
• Perfusion filter
• Screw cap
• ReadyMate aseptic connectors

Cellbag™ bioreactor containers can also be customized to suit your specific cell culture process needs.

Cellbag™ bioreactor container materials of construction

Cellbag™ bioreactor containers with Bioclear™ 10 have fluid contact layers that are a USP Class VI ethylene vinyl acetate/low density polyethylene copolymer. This composition provides biological compatibility for animal cell cultivation. Outer noncontact layers are made of low-density polyethylene, providing strength and low gas permeability.

Porous polyethylene-based perfusion filter

Perfusion Cellbag™ bioreactor containers are fitted with a porous polyethylene-based perfusion filter that floats on the medium and is used to retain cells in the bag during perfusion cultivation or medium exchange. Perfusion bags come with two filter options.

Single-use bioreactor bags available in new film

Cellbag™ bioreactor containers with Fortem film are now available for animal cell cultivation in ReadyToProcess WAVE™ rocking motion bioreactors. Fortem™ single-use film was built from scratch for bioprocessing. Fortem™ film delivers an enhanced material science profile, application performance, and supply chain security.

Documents

• Data file (PDF)