The Cellartis iPS Cell to Hepatocyte Differentiation System is a complete system for differentiation of human induced pluripotent stem (iPS) cells to hepatocytes via definitive endoderm (DE). This kit includes the Cellartis DEF-CS Culture System for expansion of undifferentiated iPS cells, the Cellartis Definitive Endoderm Differentiation Kit for differentiation to DE cells, and the Cellartis Hepatocyte Differentiation Kit for subsequent differentiation to hepatocytes.
Features
Ideal for drug metabolism and safety studies—consistently generate panels of >90% pure, functional, hiPS cell-derived hepatocytes with diverse genetic backgrounds
Customized starting materials—start with any disease-relevant iPS cell lines and create accurate liver disease models
Ready for personalized medicine—make patient-specific, disease-specific cells for therapeutic applications
Extended experimental window—hepatocytes can be used for a minimum of 11 days for functional tests
