Cardamonin, NFkB inhibitor

Product Details

Formal Name: (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one

Molecular Formula: C₁₆H₁₄O₄

Formula Weight: 270.29

CAS Number: 19309-14-9

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 5 mg/ml).

Storage: -20°C

Stability: ≥ 2 years.

Applications

NFkB inhibitor

Functions

Inhibits NF-κB activation via inhibition of IκBα degradation and phosphorylation, IκB kinase activation and NF-κB nuclear translocation. Displays anti-inflammatory activity in various models. Cell permeable.

Application Procedures

First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 5 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 2 weeks.

Research use only.

Documents

• Datasheet (PDF)
• MSDS (PDF)