BMS-202, PD-1/PD-L1 inhibitor

Product Details

Formal Name: N-[2-[[2-Methoxy-6-[(2-methyl-3-phenylphenyl)methoxy]pyridine-3-yl]methylamino]ethyl]acetamide

Alternate Names: PD-1/PD-L1 Inhibitor 2

Molecular Formula: C₂₅H₂₉N₃O₃

Formula Weight: 419.53

CAS Number: 1675203-84-5

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

Applications

PD-1/PD-L1 inhibitor

Functions

BMS-202 (1675203-84-5) inhibits (IC50 = 18nM) formation of the PD-1/PD-L1 complex via binding to PD-L1 and inducing dimerization.

Application Procedures

First dissolved in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Research use only.

Documents

• Datasheet (PDF)
• MSDS (PDF)