BAY K8644, L-type calcium channel activator

Product Details

Formal Name: (±)- Methyl 1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylate

Molecular Formula: C₁₆H₁₅F₃N₂O₄

Formula Weight: 356.30

CAS Number: 71145-03-4

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).

Storage: -20°C

Stability: ≥ 1 year.

Applications

L-type calcium channel activator

Functions

BAY K8644 is an ionotropic agent that activates L-type calcium channels by prolonging single-channel open time without affecting closed time. It acts as a vasoconstrictor, and in combination with histone methyltransferase inhibitor BIX-01294 (#MC-1335), induces reprogramming of mouse embryonic fibroblasts transduced with Oct4/Klf4.

Application Procedures

First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Research use only.

Documents

• Datasheet (PDF)
• MSDS (PDF)