Product Details
Formal Name: N-[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide
Molecular Formula: C20H17ClN2O4S
Formula Weight: 416.90
CAS Number: 2055602-83-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
P2X4 antagonist (selective)
Functions
Selective P2X4 receptor antagonist (IC50 = 211 nM HEK cellular assay; P2X4 calcium influx based assays – hIC50 = 108 nM, mIC50 = 112 nM, rIC50 = 233 nM). Displays antinociceptive and anti-inflammatory effects in mouse CFA inflammatory pain models.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Research use only.
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