Product Details
Formal Name: 2,3-Dichloro-N-(3-methoxypyrazine-2-yl)benzenesulfonamide
Molecular Formula: C11H9Cl2N3O3S
Formula Weight: 334.20
CAS Number: 566203-88-1
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to at least 25 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
CCR4 antagonist
Functions
Potent, orally bioavailable antagonist of CCR4 (pIC50 = 7.8(h), 8.0(r), 8.0(m), 7.6(d)). Inactive at CXCR1/2, CCR1, CCR2b, CCR5, CCR7, and CCR8 @ 10 µM.
Application Procedures
First dissolved in DMSO (up to at least 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Research use only.
Documents
