Aripiprazole, Dopamine receptor partial agonist

Product Details

Formal Name: 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone

Alternate Names: OPC-14597

Molecular Formula: C₂₃H₂₇Cl₂N₃O₂

Formula Weight: 448.40

CAS Number: 129722-12-9

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 5 mg/ml with warming).

Storage: RT

Stability: ≥ 2 years.

Applications

Dopamine receptor partial agonist

Functions

Clinically useful neuroleptic and antipsychotic agent. Dopamine D2 receptor antagonist and autoreceptor agonist. Improves symptoms of psychosis associated with Alzheimer’s disease. Blocks cocaine-seeking behavior without affecting other rewarding behaviors in animal models.

Application Procedures

First dissolved in DMSO (up to 30 mg/ml) or in Ethanol (up to 5 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or Ethanol may be stored at -20°C for up to 3 months.

Research use only.

Documents

• Datasheet (PDF)