Product Details
Formal Name: N-[(4-Methoxyphenyl)methyl]-N’-(5-nitro-2-thiazolyl)urea
Molecular Formula: C12H12N4O4S
Formula Weight: 308.32
CAS Number: 487021-52-3
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 30 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
GSK-3 inhibitor
Functions
Selective glycogen synthase kinase 3 (GSK-3) inhibitor, IC50 = 104 nM. Inhibits β-amyloid-mediated neurodegeneration in hippocampal slices. Anti-inflammatory activity. Cell permeable. Active in rodent models.
Application Procedures
First dissolved in DMSO (up to 30 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.
Research use only.
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