Activates JNK/SAPKs and induces c-fos and c-jun. Induces apoptosis and sensitizes cells to anoikis. Displays immunosuppressive activity, inhibiting T cell proliferation in mouse models. Inhibits consolidation of new context-specific long-term memories. Protein synthesis inhibitor (inhibits translation). Cell permeable.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.
