A/C Heterodimerizer

A/C Heterodimerizer is a membrane-permeant ligand that causes heterodimerization of proteins fused to two distinct dimerization domains—DmrA and DmrC—provided in the iDimerize Inducible Heterodimer System (Cat. #  635067) and the iDimerize Regulated Transcription System (Cat. # 635081). NOTE: The A/C Heterodimerizer is identical to the AP21967 ligand previously supplied in the ARGENT Regulated Heterodimerization Kit from ARIAD Pharmaceuticals, Inc.

Features

• Achieve small-molecule control of cellular events that are usually activated by protein heterodimerization
• Control the subcellular localization of a target protein
• A/C Heterodimerizer is identical to the AP21967 ligand
• For inducible control of transcription factors, use the iDimerize Regulated Transcription System
• Plasmid and lentiviral (Lenti-X) vector formats are available

Documents

• Safety Data Sheet (PDF)
• User Manual (PDF)
• Components
• Components
• Components

Required Products

⚠️ A Required Product (e.g. an index kit) must be purchased to use this product — order one for each unit you buy.