Collection: Mass Photometry

Mass photometry measures the mass of individual biomolecules in solution from the light they scatter: a few microliters of label-free sample at nanomolar concentration give molar mass, oligomeric state, sample purity, aggregation and binding stoichiometry in minutes, with no column, calibration standards or immobilization. Choose the TwoMP for manual benchtop work across proteins, nucleic acids and complexes (30 kDa to 5 MDa), the TwoMP Auto when you need to screen many samples or conditions unattended, and the MassFluidix HC add-on for weak or transient interactions that require micromolar concentrations. For absolute molar mass of separated species use SEC-MALS; for hydrodynamic size and polydispersity in bulk use DLS.