{"product_id":"wyatt-microviscostar-online-differential-viscometer","title":"microViscoStar Online Differential Viscometer","description":"\u003cspan\u003e\u003cp align=\"center\"\u003e\u003cimg alt=\"microViscoStar\" class=\"scale-with-grid\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/10\/microViscoStar-Hero-Neon-10-2-19.jpg\" title=\"microViscoStar-1500\" width=\"65%\"\u003e\u003c\/p\u003e\u003c\/span\u003e\n\u003cp\u003emicroViscoStar: Online differential viscometer for UHPLC.\u003c\/p\u003e\n\u003cp\u003eHighly Sensitive\u003c\/p\u003e\n\u003cp\u003eA highly sensitive, on-line differential viscometer used with \u003ca href=\"https:\/\/www.wyatt.com\/solutions\/techniques\/sec-iv-polymer-molar-mass-and-conformation.html\"\u003eSEC-MALS-IV\u003c\/a\u003e to determine the size and conformation of polymers, proteins and peptides separated by UHPLC.\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eMultiple Novel Technologies\u003c\/p\u003e\n\u003cp\u003eThe microViscoStar\u003csup\u003e™\u003c\/sup\u003e incorporates multiple novel technologies to provide the highest sensitivity, stability and solvent compatibility of any available viscometer for UHPLC. Its ease-of-use and serviceability make it the perfect companion for Wyatt's \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/microDawn-multi-angle-detector-uhplc-sec-mals.html\"\u003emicroDAWN\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e light scattering and \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/microOptilab-uhplc-refractometer-sec-mals.html\"\u003emicroOptilab\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e refractive index detectors for UHPLC.\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eAPC and UHPLC Applications\u003c\/p\u003e\n\u003cp\u003eView the webinar \u003ca href=\"https:\/\/www.wyatt.com\/library\/webinars\/development-of-a-new-online-micro-viscometer-for-apc-and-uhplc-applications.html\"\u003eDevelopment of a New Online Micro-Viscometer for APC and UHPLC Applications\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eTo learn about the technological breakthroughs implemented in the microViscoStar, download \u003ca href=\"https:\/\/wyattfiles.s3.us-west-2.amazonaws.com\/literature\/white-papers\/WP9005-ViscoStar-Innovations-in-Online-Viscometry.pdf\" target=\"_blank\"\u003eViscoStar: Innovations in Online Viscometry for GPC\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eAnother path to polymer and protein characterization: SEC-MALS-IV\u003c\/p\u003e\n\u003cp\u003eWhen coupled with UHPLC size-exclusion chromatography and a compatible concentration detector such as the \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/optilab-refractive-index-detector.html\"\u003eOptilab\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e, the microViscoStar derives the intrinsic viscosity (IV) of polymers, rapidly and with minimal sample and solvent consumption. An inherently valuable physico-chemical property in itself, IV is best utilized together with molar mass information from a microDAWN multi-angle light scattering (SEC-MALS-IV) to  derive the \u003ci\u003ehydrodynamic radius\u003c\/i\u003e, \u003ci\u003econformation\u003c\/i\u003e, and \u003ci\u003ebranching ratio\u003c\/i\u003e of a macromolecule in solution.\u003c\/p\u003e\n\u003cdiv class=\"column one-second\"\u003e\n\u003cp\u003eKey benefits of the microViscoStar\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eHigh sensitivity\u003c\/b\u003e, equivalent to 5 ng of 100 kDa polystyrene in THF at 1.0 mL\/min injected onto a standard GPC column\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eHigh dynamic range\u003c\/b\u003e of over 135,000:1. The full measurement range corresponds to over 13 mg\/mL of 100 kDa polystyrene in THF\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eExtended solvent compatibility\u003c\/b\u003e with all-316 stainless steel transducers\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eTemperature range\u003c\/b\u003e from 4 °C to 70 °C for polymers or proteins that require a range of temperatures\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eMinimal band broadening\u003c\/b\u003e thanks to fast pressure transducers\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePump pulse suppression\u003c\/b\u003e to below 4 Pa (hardware alone) or 1 Pa (hardware + software) without loss of chromatographic resolution \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eAutomated capillary bridge tuning\u003c\/b\u003e with no moving parts, to guarantee a perfectly balanced bridge, every run\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eEnhanced thermal stability\u003c\/b\u003e with drift of \u0026lt;1.25 Pa\/hour\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cbr\u003e \n\u003cp\u003eSEC-IV without MALS?\u003c\/p\u003e\n\u003cp\u003eYes, as much as we love MALS for optimal polymer analysis, it's true that there are occasions when it just won't fit the bill.\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eUniversal calibration\u003c\/i\u003e is a parallel technique to SEC-MALS for determining molecular weight, commonly used to characterize linear polymers. While universal calibration overcomes some of the problematic issues  associated with column calibration by reference molecules, it does not account for non-ideal column behavior caused by chemical solute-column interactions or hyperbranching. \u003c\/p\u003e\n\u003cp\u003eUniversal calibration is particularly-well suited to replace MALS for:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStrongly fluorescent polymers\u003c\/b\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eWeakly-scattering\u003c\/b\u003e polymer\/solvent systems with very low \u003ci\u003edn\/dc\u003c\/i\u003e values\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003ci\u003eThe Mark-Houwink-Sakurada relationship\u003c\/i\u003e makes use of empirical relationships between intrinsic viscosity and molar mass, specific to each polymer and solvent, to estimate molar mass from SEC-IV measurements. Of course, the best way to determine MHS coefficients is to measure them using SEC-MALS-IV and ASTRA!\u003c\/p\u003e\n\u003cp\u003eGo to the \u003cb\u003eAdvanced Technology\u003c\/b\u003e tab to learn more about the unique features of the microViscoStar.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"column one-second\"\u003e\n\u003cp align=\"center\"\u003e\u003cimg alt=\"microViscostar pump pulse  suppression\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/05\/pump-pulse-suppression-with-inset.jpg\" title=\"microViscostar pump pulse suppression\"\u003e\u003c\/p\u003e\n\u003cp align=\"left\" style=\"color:#075c97;font-size:14px;padding-left:30px\"\u003ePatented pulse compensation technology in the microViscoStar eliminates pump fluctuations. At the hardware level, the bridge is impedance-matched for dynamic balance, greatly reducing the effect of pump pulses. An additional layer of software filtering eliminates residual pump pulses.\u003c\/p\u003e\n\u003cfigure style=\"margin-left: 15px; text-align: center;\"\u003e\u003cimg alt=\"microViscoStar measurements of epoxy resins\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/05\/mVS-epoxy.png\" title=\"microViscoStar measurements of \n        epoxy resins\"\u003e\n\u003cp align=\"left\" style=\"color:#075c97;font-size:14px;padding-left:30px\"\u003eThe microVisoStar maintains the narrow peaks and excellent resolution of UHPLC with maximum sensitivity. In this graph, the refractive index and specific viscosity chromatograms of an epoxy resin are overlaid with the molar mass and intrinsic viscosity results calculated from MALS and specific viscosity data, respectively, at each elution volume. The sample was separated on four Waters\u003csup\u003e®\u003c\/sup\u003e APC XT columns in series with pore sizes of 45, 125, 450 and 900 Å.\u003c\/p\u003e\u003c\/figure\u003e\n\u003c\/div\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSensitivity (minimum detectable sample)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e5 ng of 100 kDa polystyrene in THF at 1 mL\/min, under typical UHPLC-SEC conditions\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDifferential pressure noise\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u0026lt; 0.05 Pa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDifferential pressure range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e6.9 kPa, protected against overpressure\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDynamic range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e135,000:1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLinearity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0.5% of full scale\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDifferential pressure drift\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u0026lt; 1.25 Pa\/hr\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCapillary bridge autobalance\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eThermal, leak-free mechanism\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSample shear rate\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e15000 Hz with water at 1 mL\/min\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMax. flow rate\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAqueous: 1 mL\/min; THF: 1 mL\/min\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDelay volume options\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e5.4 mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMax. permissible pressure inlet to outlet\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e3000 kPa (435 psi)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eWetted Materials\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e316 stainless steel, PTFE, zirconium silicate, Kalrez , Inconel, 26-1 Stainless Steel, Nickel\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRange\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e4 °C to 70 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStability\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u0026lt;0.005°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAmbient Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0 ºC to 40 ºC, 20% to 70% RH\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDigital Output\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e20 bits @ 10 Hz\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eInputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAutoinject contact closure, Alarm In, Analog In: 2 differential inputs, 16 bits resolution, range -10 V to +10 V\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eOutputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAutoinject Retransmit, Alarm Out, Recycle Out\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCommunications\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eEthernet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFront Panel Display\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e7\" (178 mm), high-resolution, multi-touch display for viewing\/setting signals, instrument settings and diagnostics.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDimensions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e60 cm (L) x 36 cm (W) x 17 cm (H)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.wyatt.com\/products\/microviscostar-brochure-request.html\" target=\"_blank\"\u003eBrochure\u003c\/a\u003e\u003c\/p\u003e","brand":"Wyatt Technology","offers":[{"title":"Standard","offer_id":46488398823503,"sku":"WUV4","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Standard Delay Column","offer_id":46488398856271,"sku":"WUV4-01","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/microViscoStar-Hero-Neon-10-2-19_aca2bc34-e001-4882-ae70-6f70937771f3.jpg?v=1787675383","url":"https:\/\/www.danyel.co.il\/products\/wyatt-microviscostar-online-differential-viscometer","provider":"danyel biotech","version":"1.0","type":"link"}