{"product_id":"tau-phospho-thr205-antibody-tbs10047-50ul","title":"Tau(Phospho-Thr205) Antibody","description":"\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003e\u003cu\u003eDescription\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eThe Tau (Phospho-Thr205) Antibody could play a role in the establishment and maintenance of neuronal polarity by promoting microtubule assembly and stability. It appears that tau serves as a linker protein between these processes, as the C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components. Tau localization inside the neuronal cell, specifically in the centrosome-defined area of the cell body, predetermines axonal polarity. While longer isoforms may primarily contribute to the stabilization of the cytoskeleton, shorter isoforms permit greater plasticity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003e \u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003e\u003cu\u003eProduct Details\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHost Species:\u003c\/strong\u003e Rabbit\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eClonality:\u003c\/strong\u003e Polyclonal\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurification: \u003c\/strong\u003eAntibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e WB IHC, ELISA\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSpecies Reactivity:\u003c\/strong\u003e Hu Ms Rt\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSpecificity:\u003c\/strong\u003e The antibody detects endogenous level of Tau only when phosphorylated at threonine 205.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImmunogen Type:\u003c\/strong\u003e Peptide-KLH\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImmunogen Description:\u003c\/strong\u003e  Peptide sequence around phosphorylation site of threonine 205 (P-G-T(p)-P-G) derived from Human Tau.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAccession No.:\u003c\/strong\u003e Swiss-Prot: P10636NCBI Protein: NP _001116538.1\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUniprot:\u003c\/strong\u003e P10636.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 1.0mg\/ml\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFormulation:\u003c\/strong\u003e Supplied at 1.0mg\/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003e\u003cu\u003eApplications\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePredicted MW:\u003c\/strong\u003e 48 62 78 kd\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWestern blotting:\u003c\/strong\u003e 1:500~1:1000\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImmunohistochemistry:\u003c\/strong\u003e 1:50~1:100\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 13px; font-weight: 700; text-transform: uppercase;\"\u003e\u003cstrong\u003eResearch use only.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/wp-content\/uploads\/2024\/04\/TBS10047-Tau_Phospho-Thr205_Antibody_Data-Sheet.pdf\"\u003eDatasheet (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/wp-content\/uploads\/2024\/04\/TBS10047-Tau_Phospho-Thr205_Antibody_MSDS-2024.pdf\"\u003eMSDS (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"TriBioScience","offers":[{"title":"50UL","offer_id":45986345484367,"sku":"TBS10047-50UL","price":1199.0,"currency_code":"ILS","in_stock":true},{"title":"100UL","offer_id":45986345517135,"sku":"TBS10047-100UL","price":2268.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/TBS10047.png?v=1782809131","url":"https:\/\/www.danyel.co.il\/products\/tau-phospho-thr205-antibody-tbs10047-50ul","provider":"danyel biotech","version":"1.0","type":"link"}