{"product_id":"sophia-ddm-lymphoma-solution-lys-bs0116","title":"SOPHiA DDM™ Lymphoma Solution (LYS)","description":"\u003cp\u003eThe SOPHiA DDM™ Lymphoma Solution (LYS) is a comprehensive capture-based application designed to detect and analyze genomic alterations on 54 genes associated with various B- and T-cell lymphomas.\u003c\/p\u003e\u003cp\u003eSample-to-report bundle: capture-based target enrichment and library preparation kit combined with the analytical capabilities of the SOPHiA DDM™ Platform.\u003c\/p\u003e\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eGene content\u003c\/th\u003e\n\u003ctd\u003e54 genes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eKey biomarkers\u003c\/th\u003e\n\u003ctd\u003eCREBBP, EP300, EZH2, MEF2B, MYD88, MYC, BRAF\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eDiseases covered\u003c\/th\u003e\n\u003ctd\u003eB- and T-cell lymphomas such as diffuse large B-cell, follicular, mantle cell, and Burkitt lymphomas\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eDetected variants\u003c\/th\u003e\n\u003ctd\u003eSNVs\u003cbr\u003eIndels\u003cbr\u003eGene amplifications (47 genes)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSample type\u003c\/th\u003e\n\u003ctd\u003eFFPE, blood, and bone marrow\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStarting material\u003c\/th\u003e\n\u003ctd\u003e50 ng DNA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eTarget region size\u003c\/th\u003e\n\u003ctd\u003e118 Kb\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSequencer compatibility\u003c\/th\u003e\n\u003ctd\u003eIllumina MiSeq® and NextSeq®\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eLibrary preparation time\u003c\/th\u003e\n\u003ctd\u003e1.5 days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eAnalysis time from FASTQ\u003c\/th\u003e\n\u003ctd\u003e4 hours\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eRegulatory status\u003c\/th\u003e\n\u003ctd\u003eResearch Use Only (RUO)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\u003ch2\u003eKey Features\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eGain a complete view of Lymphoid Malignancies\u003c\/strong\u003e – Go from sample to report with SOPHiA DDM™ for Lymphoid Malignancies. Leverage our flexible platform that offers a comprehensive range of guideline-driven, ready-to-use, and customizable next-generation sequencing (NGS)-based applications to enhance your genomic profiling capabilities.\u003c\/p\u003e\u003ch2\u003eWorkflow\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eCharting the course to solve lymphoid cases\u003c\/strong\u003e – Streamline your analysis with an accurate and adaptable workflow.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eA wave of insights for every laboratory\u003c\/strong\u003e – Streamline your blood cancer analysis workflow from sample to comprehensive, customized report.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFlexible and scalable library preparation\u003c\/strong\u003e – Rely on robust sequencing across multiple applications using one universal and automated protocol.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAccurate variant detection and annotation\u003c\/strong\u003e – Precisely detect challenging genomic variants thanks to the power of our proprietary algorithms.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCustomizable reporting\u003c\/strong\u003e – Quickly prepare comprehensive reports tailored to your needs.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eAnalytics\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eTurning data into insights—it’s in our blood\u003c\/strong\u003e – Gain deeper insights into lymphoid malignancies by accurately assessing even the most challenging molecular biomarkers with the advanced power of SOPHiA DDM™'s proprietary algorithms.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSensitive SNV and Indel detection\u003c\/strong\u003e – Accurately identify single nucleotide variants (SNVs) and small insertions\/deletions (Indels) in lymphoid malignancies, even in challenging samples. PEPPER™’s sophisticated algorithm differentiate true signal from noise, providing you with reliable results to guide your decisions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAccurate CNV calling\u003c\/strong\u003e – Gain crucial insights into the genomic alterations driving lymphoid malignancies with MUSKAT™. Our copy number variation (CNV) calling algorithm adapts to experimental conditions and performs double normalization to call CNVs missed by other tools.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRobust variant annotation\u003c\/strong\u003e – Confidently interpret the significance of genomic variants in lymphoid malignancies with MOKA™. Our robust annotation algorithm draws from curated databases and uses de novo analytics to provide insights on the likely effects and pathogenicity of genomic variants.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExplore IGH and IGL rearrangement\u003c\/strong\u003e – SOPHiA GENETICS worked with IDIBAPS to enable IgCaller companion software to be used with SOPHiA DDM™ Community CLL Clonality Solution.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eProduct code\u003c\/th\u003e\n\u003cth\u003eReactions\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eBS0116ILLRSMY10-16\u003c\/td\u003e\n\u003ctd\u003e16\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBS0116ILLRSMY10-32\u003c\/td\u003e\n\u003ctd\u003e32\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003cem\u003eFor Research Use Only. Not for use in diagnostic procedures.\u003c\/em\u003e\u003c\/p\u003e","brand":"SOPHiA GENETICS","offers":[{"title":"16 reactions","offer_id":46798543061071,"sku":"BS0116ILLRSMY10-16","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"32 reactions","offer_id":46798543093839,"sku":"BS0116ILLRSMY10-32","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/sophia-genetics-logo.png?v=1789657266","url":"https:\/\/www.danyel.co.il\/products\/sophia-ddm-lymphoma-solution-lys-bs0116","provider":"danyel biotech","version":"1.0","type":"link"}