{"product_id":"seracare-seraseq-ffpe-hrd-reference-material-0710-2643","title":"Seraseq® FFPE HRD Reference Material","description":"\u003cp\u003eGenomic instability resulting from homologous recombination DNA repair deficiency (HRD) is a response biomarker to assess ovarian and breast cancer patient eligibility for PARP inhibitor and platinum-based therapies. HRD measurements have the potential to improve cancer therapy, however standardizing and democratizing HRD measurements remains challenging. LGC SeraCare has developed HRD reference materials to support the development, validation, and routine determination of HRD status in cancer patients.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e• Derived from tumor and matched-normal human cell lines\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e• Blended to ~65% tumor content with SNP-matched normal cell lines\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e• Additional biosynthetic single-nucleotide variants (SNVs) of 4 homologous recombination repair (HRR) genes\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e• 10 µm FFPE curl with DNA yield \u0026gt;100 ng per curl\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e• Full-process FFPE format reference material validated by NGS and microarray assays with various HRD algorithms (see the Data Sheet for more details) \u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e• Manufactured in GMP-compliant, ISO 13485-certified facilities\u003c\/p\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.seracare.com\/globalassets\/seracare-resources\/ps-0710-2643-2645-seraseq-ffpe-hrd-rm.pdf\" target=\"_blank\" rel=\"noopener\"\u003eSeraseq FFPE HRD (High-Positive, Low-Positive, Negative) Reference Material Product Sheet (Product Sheet)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.seracare.com\/globalassets\/seracare-resources\/ds-0710-2643-2645-seraseq-ffpe-hrd-rm.pdf\" target=\"_blank\" rel=\"noopener\"\u003eSeraseq FFPE HRD (High-Positive, Low-Positive, Negative) Reference Material (Data Sheet)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.seracare.com\/globalassets\/seracare-resources\/pi-0710-2643-2645-seraseq-ffpe-hrd-rm.pdf\" target=\"_blank\" rel=\"noopener\"\u003eSeraseq FFPE HRD (High-Positive, Low-Positive, Negative) Reference Material Package Insert (Package Insert)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.seracare.com\/globalassets\/seracare-resources\/tss-0710-2879.2880.2881-seraseq-gdna-hrd-mix.xlsx\" target=\"_blank\" rel=\"noopener\"\u003eTechnical Spreadsheet for Seraseq HRD Reference Materials (Technical Spreadsheet)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.seracare.com\/globalassets\/seracare-resources\/sds-seraseq-ffpe.pdf\" target=\"_blank\" rel=\"noopener\"\u003eSeraseq FFPE Safety Data Sheet (Safety Data Sheet)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eSize\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e0710-2643\u003c\/td\u003e\n\u003ctd\u003eSeraseq® FFPE HRD High-Positive RM\u003c\/td\u003e\n\u003ctd\u003e1 x 10 µm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e0710-2644\u003c\/td\u003e\n\u003ctd\u003eSeraseq® FFPE HRD Negative RM\u003c\/td\u003e\n\u003ctd\u003e1 x 10 µm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e0710-2645\u003c\/td\u003e\n\u003ctd\u003eSeraseq® FFPE HRD Low-Positive RM\u003c\/td\u003e\n\u003ctd\u003e1 x 10 µm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"SeraCare","offers":[{"title":"High-Positive","offer_id":46798512291919,"sku":"0710-2643","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Negative","offer_id":46798512324687,"sku":"0710-2644","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Low-Positive","offer_id":46798512357455,"sku":"0710-2645","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/0710-2643.jpg?v=1789655887","url":"https:\/\/www.danyel.co.il\/products\/seracare-seraseq-ffpe-hrd-reference-material-0710-2643","provider":"danyel biotech","version":"1.0","type":"link"}