{"product_id":"seracare-seraseq-ctdna-mutation-mix-v4-0710-3100","title":"Seraseq® ctDNA Mutation Mix v4","description":"\u003cp\u003eAs liquid biopsy assays gain acceptance for a growing variety of clinical applications, an acute need for highly multiplexed reference materials bearing a broad range of clinically relevant variant types has arisen. But searching for useful remnant patient specimens is prohibitively time-consuming, and single plex cell lines are inefficient and add unnecessary expense.\u003c\/p\u003e\n\u003cp\u003eSeraseq ctDNA v4 reference materials are purpose-built to accelerate the thorough validation and clinical implementation of NGS-based ctDNA assays. Seraseq ctDNA v4 contains an unprecedented 93 variants including SNPs, indels, translocations and CNVs. Seraseq ctDNA v4 is manufactured with a new fragmentation process which results lower background than previous Seraseq ctDNA offerings to support greater confidence at low variant allele frequencies. These orthogonally validated truth-set materials can trim weeks or even months off your assay validation timeline with the most complete coverage of actionable variant types in a single reference sample. With the input of recognized clinical genomics experts, the Seraseq ctDNA v4 Reference Materials focus on clinically relevant variants that provide actionable feedback about patient samples.\u003c\/p\u003e\n\u003cp\u003eFEATURES AND BENEFITS\u003c\/p\u003e\n\u003cp\u003e93 unique multiplexed variants in 71 genes, covering 43 SNVs, 19 deletions, 5 insertions, 4 INDELs, 12 CNVs, and 10 translocations for the broadest coverage of clinically relevant variant types in a single reference material\u003c\/p\u003e\n\u003cp\u003eFour different variant allele frequencies (VAF) – WT (0%), 0.1%, 0.5%, and 5% - challenge your limit-of-detection or match typical AF of solid tumor NGS assays\u003c\/p\u003e\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eFragment Size\u003c\/td\u003e\n\u003ctd\u003e155-200 bp peak\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eConcentration\u003c\/td\u003e\n\u003ctd\u003e10 ng\/µL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFill Volume\u003c\/td\u003e\n\u003ctd\u003e25 µL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAmount\u003c\/td\u003e\n\u003ctd\u003e250 ng (single vial)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e# of Vials\u003c\/td\u003e\n\u003ctd\u003e1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMatrix\u003c\/td\u003e\n\u003ctd\u003ePurified DNA in Buffer (Tris\/EDTA)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.seracare.com\/globalassets\/seracare-resources\/ps-0710-3097.3099.3100.3101-seraseq-ctdna-mutation-mix-v4.pdf\" target=\"_blank\" rel=\"noopener\"\u003eSeraseq ctDNA v4 Reference Materials Product Sheet (Product Sheet)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.seracare.com\/globalassets\/seracare-resources\/pi-0710-3097.3099.3100.3101-seraseq-ctdna-mutation-mix-v4.pdf\" target=\"_blank\" rel=\"noopener\"\u003ePackage Insert for Seraseq ctDNA Mutation Mix v4 (Package Insert)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.seracare.com\/globalassets\/seracare-resources\/ts-0710-3097.3099.3100.3101-seraseq-ctdna-mutation-mix-v4.xlsx\" target=\"_blank\" rel=\"noopener\"\u003eTechnical Spreadsheet for Seraseq® ctDNA v4 Reference Materials (Technical Spreadsheet)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.seracare.com\/globalassets\/seracare-resources\/nrl-0710-3088.3089.3181-3184-seraseq-ctdna-mutation-mix.pdf\" target=\"_blank\" rel=\"noopener\"\u003eSeraseq ctDNA Mutation Mix Non-Requirement Letter (SDS Non-Requirement Letter)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eSize\u003c\/th\u003e\n\u003cth\u003e# of Variants\u003c\/th\u003e\n\u003cth\u003eAllele Frequency\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e0710-3100\u003c\/td\u003e\n\u003ctd\u003eSeraseq® ctDNA Mutation Mix v4 AF5%\u003c\/td\u003e\n\u003ctd\u003e1 x 25 µL\u003c\/td\u003e\n\u003ctd\u003e93\u003c\/td\u003e\n\u003ctd\u003e5%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e0710-3099\u003c\/td\u003e\n\u003ctd\u003eSeraseq® ctDNA Mutation Mix v4 AF0.5%\u003c\/td\u003e\n\u003ctd\u003e1 x 25 µL\u003c\/td\u003e\n\u003ctd\u003e93\u003c\/td\u003e\n\u003ctd\u003e0.5%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e0710-3097\u003c\/td\u003e\n\u003ctd\u003eSeraseq® ctDNA Mutation Mix v4 AF0.1%\u003c\/td\u003e\n\u003ctd\u003e1 x 25 µL\u003c\/td\u003e\n\u003ctd\u003e93\u003c\/td\u003e\n\u003ctd\u003e0.1%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e0710-3101\u003c\/td\u003e\n\u003ctd\u003eSeraseq® ctDNA Mutation Mix v4 WT\u003c\/td\u003e\n\u003ctd\u003e1 x 25 µL\u003c\/td\u003e\n\u003ctd\u003e0 (Wild-Type)\u003c\/td\u003e\n\u003ctd\u003eWild-Type\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"SeraCare","offers":[{"title":"AF5%","offer_id":46798512914511,"sku":"0710-3100","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"AF0.5%","offer_id":46798512947279,"sku":"0710-3099","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"AF0.1%","offer_id":46798512980047,"sku":"0710-3097","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"WT","offer_id":46798513012815,"sku":"0710-3101","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/0710-3100.jpg?v=1789655911","url":"https:\/\/www.danyel.co.il\/products\/seracare-seraseq-ctdna-mutation-mix-v4-0710-3100","provider":"danyel biotech","version":"1.0","type":"link"}