{"product_id":"seracare-seraseq-carrier-screening-dna-mix-0730-0569","title":"Seraseq® Carrier Screening DNA Mix","description":"\u003cp\u003eThe Seraseq Carrier Screening DNA Mix is a reference material intended for use in the development, validation, and evaluation of routine performance of Next Generation Sequencing (NGS) carrier screening assays (and other molecular assays) that identify inherited (germline) variants in genes associated with monogenic diseases.\u003cbr\u003eThis is a highly multiplexed and comprehensive reference material containing 54 clinically important SNVs, deletions and duplications occurring in inherited hemoglobinopathies, deafness, heart disease, immunodeficiency, neuromuscular and treatable metabolic disorders.\u003c\/p\u003e\n\u003cp\u003eFEATURES AND BENEFITS\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDevelop and validate carrier screening-based NGS assays with confidence using a highly multiplexed reference material containing important monogenic disorder biomarkers.\u003c\/li\u003e\n\u003cli\u003eContains 54 clinically important variants from 48 genes associated with the most common monogenic disorders: Cystic Fibrosis, Spinal Muscular Atrophy (SMA), α- and β-thalassemia, congenital deafness, fragile X syndrome, sickle cell disease, Tay–Sachs disease, Gaucher disease, Phenylketonuria, Cardiomyopathy, Smith–Lemli–Opitz syndrome and many more.\u003c\/li\u003e\n\u003cli\u003eVariants are present within a single well-characterized genomic background (GM24385) at clinically relevant allele frequencies, precisely quantitated by digital PCR and orthogonally verified by NGS.\u003c\/li\u003e\n\u003cli\u003eManufacturing of large batches with long shelf-life allows for repeated use of the same lot for validation, or assay performance assessment over time.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e# of genes\u003c\/td\u003e\n\u003ctd\u003e48 genes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e# of mutations\u003c\/td\u003e\n\u003ctd\u003e54 variants (not including those present in the GM24385 background)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat\u003c\/td\u003e\n\u003ctd\u003e1 mM Tris, 0.1 mM EDTA, pH 8.0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSize\u003c\/td\u003e\n\u003ctd\u003e1 x 20 µL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNominal Concentration\u003c\/td\u003e\n\u003ctd\u003e30 ng\/µL (Please refer to the technical report for the batch-specific concentration)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.seracare.com\/globalassets\/seracare-resources\/ps-0730-0569-seraseq-carrier-screening-dna-mix.pdf\" target=\"_blank\" rel=\"noopener\"\u003eSeraseq Carrier Screening DNA Mix Product Sheet (Product Sheet)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.seracare.com\/globalassets\/seracare-resources\/pi-0730-0569-seraseq-carrier-screening-dna-mix.pdf\" target=\"_blank\" rel=\"noopener\"\u003eSeraseq Carrier Screening DNA Mix (Package Insert)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.seracare.com\/globalassets\/seracare-resources\/ts-0730-0569-seraseq-carrier-screening-dna-mix.xlsx\" target=\"_blank\" rel=\"noopener\"\u003eTechnical Spreadsheet for Seraseq Carrier Screening DNA Mix (Technical Spreadsheet)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.seracare.com\/globalassets\/seracare-resources\/nrl-0730-0567.0570-seraseq-gdna-brca.pdf\" target=\"_blank\" rel=\"noopener\"\u003eSeraseq gDNA BRCA1 Non-Requirement Letter (SDS Non-Requirement Letter)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eSize\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003e0730-0569\u003c\/td\u003e\n\u003ctd\u003eSeraseq® Carrier Screening DNA Mix\u003c\/td\u003e\n\u003ctd\u003e1 x 20 µL\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"SeraCare","offers":[{"title":"Default Title","offer_id":46798515961935,"sku":"0730-0569","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/0730-0569.jpg?v=1789656030","url":"https:\/\/www.danyel.co.il\/products\/seracare-seraseq-carrier-screening-dna-mix-0730-0569","provider":"danyel biotech","version":"1.0","type":"link"}