{"product_id":"sensor-chip-sa-br100032","title":"Sensor Chip SA","description":"\u003cp\u003eThis high-affinity streptavidin (SA) sensor chip immobilizes biotinylated molecules for surface plasmon resonance (SPR) interaction analysis on Biacore systems.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eVersatile: immobilizes biotinylated peptides, proteins, nucleic acids, or carbohydrates\u003c\/li\u003e\n\u003cli\u003eReady-to-use: streptavidin is pre-immobilized, ready for fast, high-affinity ligand capture\u003c\/li\u003e\n\u003cli\u003eRobust: streptavidin-biotin is one of the strongest non-covalent interactions in nature\u003c\/li\u003e\n\u003cli\u003eNon-covalent: a convenient alternative for ligands refractory to covalent immobilization\u003c\/li\u003e\n\u003cli\u003eStandardized ligand orientation: controlled biotinylation enables oriented capture\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eStreptavidin-biotin capture\u003c\/p\u003e\n\n\u003cp\u003eSensor Chip SA provides a surface of streptavidin covalently attached to a carboxymethyldextran matrix. Dissociation of biotinylated ligands from the surface of the chip is generally negligible during the course of a Biacore analysis because the affinity of streptavidin for biotin is extremely high, with an equilibrium dissociation constant of about 10-15 M. High binding capacity, reproducibility, and chemical resistance give excellent performance over a broad range of applications. The surface of \u003ca href=\"https:\/\/www.cytivalifesciences.com\/en\/us\/knowledge-center\/Sensor-chips\"\u003eSensor Chip\u003c\/a\u003e SA is resistant to 1-minute pulses of many agents commonly used in SPR sensor chip washing and regeneration protocols.\u003c\/p\u003e\n\n\u003cp\u003eBiacore Sensor Chip SA applications\u003c\/p\u003e\n\n\u003cp\u003eBiotin has become a popular molecular tag for capture and interaction studies because it is stable and rarely interferes with target activity or structure due to its small size. Biotin can be conveniently conjugated to a wide range of target molecules by chemical or enzymatic means. Applications for Sensor Chip SA are therefore broad. Examples include:\u003c\/p\u003e\n\n\u003cul\u003e\n\t\u003cli\u003e\u003ca href=\"\/solutions\/protein-research\/knowledge-center\/surface-plasmon-resonance\/characterizing-protac-ternary-complex-formation-using-biacore-spr-systems\"\u003echaracterizing PROTAC ternary complex formation\u003c\/a\u003e\u003c\/li\u003e\n\t\u003cli\u003e\u003ca href=\"https:\/\/www.jstage.jst.go.jp\/article\/analsci\/20\/4\/20_4_611\/_pdf\/-char\/en\" target=\"_blank\"\u003escreening of endocrine-disrupting chemicals\u003c\/a\u003e\u003c\/li\u003e\n\t\u003cli\u003e\u003ca href=\"https:\/\/www.jbc.org\/content\/281\/25\/17446.full.pdf\" target=\"_blank\"\u003eelucidating DNA- and RNA- mediated mechanisms of catechins in cancer prevention\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eSensor chip formats for Biacore systems\u003c\/p\u003e\n\n\u003cp\u003eBiacore sensor chips are available in two formats:\u003c\/p\u003e\n\n\u003cul\u003e\n\t\u003cli\u003eSeries S sensor chips are for use with Biacore 1 series, Biacore 8 series, Biacore S200, Biacore T200, and Biacore 4000 SPR systems.\u003c\/li\u003e\n\t\u003cli\u003eSensor chips not designated with Series S are designed for Biacore X100 and Biacore C SPR systems.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/d3.cytivalifesciences.com\/prod\/IFU\/22060734.pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"Biacore 1K, Biacore 1K+,  Biacore 1S+, Biacore 8K,  Biacore 8K+, Biacore T200, Biacore S200,  Biacore 4000 \/ 1 sensor chip \/ Series S","offer_id":45982220091471,"sku":"29104992","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Biacore 1K, Biacore 1K+,  Biacore 1S+, Biacore 8K,  Biacore 8K+, Biacore T200, Biacore S200,  Biacore 4000 \/ 3 sensor chips \/ Series S","offer_id":45982220124239,"sku":"BR100531","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Biacore 1K, Biacore 1K+,  Biacore 1S+, Biacore 8K,  Biacore 8K+, Biacore T200, Biacore S200,  Biacore 4000 \/ 10 sensor chips \/ Series S","offer_id":45982220157007,"sku":"29699621","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Biacore X100, Biacore C \/ 1 sensor chip \/ Classic","offer_id":45982220189775,"sku":"BR100398","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Biacore X100, Biacore C \/ 3 sensor chips \/ Classic","offer_id":45982220222543,"sku":"BR100032","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/oiYBNVMGTUWJOdTmX9pTgg-original-png_de766a0a-c5e4-420e-af05-cdaaaf024846.png?v=1785959162","url":"https:\/\/www.danyel.co.il\/products\/sensor-chip-sa-br100032","provider":"danyel biotech","version":"1.0","type":"link"}