{"product_id":"sensor-chip-cm5-29149604","title":"Sensor Chip CM5","description":"\u003cp\u003eBiacore Sensor Chip CM5 supports a range of immobilization chemistries to capture nucleic acids, peptides, antibodies, proteins, carbohydrates, or chemical compounds for interaction analysis from research to discovery, development \u0026amp; quality control.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFirst choice for immobilization via -NH2, -SH, -CHO, -OH, or -COOH groups.\u003c\/li\u003e\n\u003cli\u003eAttach proteins, antibodies, nucleic acids, carbohydrates, and small molecules (\u0026lt;1000 Da).\u003c\/li\u003e\n\u003cli\u003eCompatible with a wide range of applications from basic research to quality control.\u003c\/li\u003e\n\u003cli\u003eSuitable for ligand fishing and fragment-based drug discovery (FBDD).\u003c\/li\u003e\n\u003cli\u003eHigh immobilization capacity permits a broad range of capture densities.\u003c\/li\u003e\n\u003cli\u003eObtain real-time data on binding specificity, affinity, kinetics, concentration and more.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBiacore Sensor Chip CM5 Matrix\u003c\/p\u003e\n\n\u003cp\u003eThe CM5 sensor chip carries a matrix of carboxymethylated dextran covalently attached to a gold surface. Molecules can be covalently coupled to the sensor surface by exploiting available amine, thiol, aldehyde, or carboxyl functional groups on the ligand. The CM5 dextran matrix extends about 100 nm from the gold surface, and is flexible, allowing relatively free movement of attached ligands.\u003c\/p\u003e\n\n\u003cp\u003eAn exceptionally versatile chip for SPR interaction analysis\u003c\/p\u003e\n\n\u003cp\u003eSensor Chip CM5 is the most versatile and widely used dextran-based chip, suitable for most general-purpose surface plasmon resonance (SPR) applications. Carboxymethyl surface chemistry supports the study of many different types of ligands and binding partners–from small organic molecules, such as drug candidates, through to large molecular assemblies and even whole viruses. High binding capacity gives a high response, advantageous for capture assays and for interactions involving small molecules. High surface stability provides accuracy and precision, and allows repeated analysis on the same surface.\u003c\/p\u003e\n\n\u003cp\u003eApplication examples include:\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/dmm3bwsv3\/AssetStream.aspx?mediaformatid=10061\u0026amp;destinationid=10016\u0026amp;assetid=29958\"\u003eFBDD-based screening for novel drugs against Hepatitis C virus (HCV)\u003c\/a\u003e\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/dmm3bwsv3\/AssetStream.aspx?mediaformatid=10061\u0026amp;destinationid=10016\u0026amp;assetid=27017\"\u003eSurface plasmon resonance-based determination of adenovirus concentration on Biacore T200\u003c\/a\u003e\u003c\/p\u003e\n\n\u003cp\u003eSensor chip formats for Biacore systems\u003c\/p\u003e\n\n\u003cp\u003eBiacore sensor chips are available in two formats:\u003c\/p\u003e\n\n\u003cul\u003e\n\t\u003cli\u003eS series sensor chips are for use with Biacore 1 series, Biacore 8 series, Biacore T200, Biacore S200 and Biacore 4000 SPR systems.\u003c\/li\u003e\n\t\u003cli\u003eSensor chips not designated with S series are designed for Biacore X100, and Biacore C SPR systems.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/d3.cytivalifesciences.com\/prod\/IFU\/22064823.pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"Biacore 1K, Biacore 1K+,  Biacore 1S+, Biacore 8K,  Biacore 8K+, Biacore T200, Biacore S200,  Biacore 4000 \/ 1 sensor chip \/ Series S","offer_id":45982219698255,"sku":"29104988","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Biacore 1K, Biacore 1K+,  Biacore 1S+, Biacore 8K,  Biacore 8K+, Biacore T200, Biacore S200,  Biacore 4000 \/ 3 sensor chips \/ Series S","offer_id":45982219731023,"sku":"BR100530","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Biacore 1K, Biacore 1K+,  Biacore 1S+, Biacore 8K,  Biacore 8K+, Biacore T200, Biacore S200,  Biacore 4000 \/ 10 sensor chips \/ Series S","offer_id":45982219763791,"sku":"29149603","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Biacore X100, Biacore C \/ 1 sensor chip \/ Classic","offer_id":45982219796559,"sku":"BR100399","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Biacore X100, Biacore C \/ 3 sensor chips \/ Classic","offer_id":45982219829327,"sku":"BR100012","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Biacore X100, Biacore C \/ 10 sensor chips \/ Classic","offer_id":45982219862095,"sku":"29149604","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-34616-original-png_5f79c42f-7462-4ee4-a296-3e85e873f53c.png?v=1785959156","url":"https:\/\/www.danyel.co.il\/products\/sensor-chip-cm5-29149604","provider":"danyel biotech","version":"1.0","type":"link"}