{"product_id":"recombinant-human-cd40lg-protein-tbp0112-10ug","title":"Recombinant human CD40LG protein","description":"\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003eDescription\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eCD40 Ligand, also known as CD40L, is a member of the tumor necrosis factor (TNF) superfamily. It is primarily expressed on activated CD4+ T cells, but can also be found on a small proportion of CD8+ T cells, platelets, B cells, basophils, eosinophils, NK cells, macrophages, dendritic cells, and smooth muscle cells. CD40L is implicated in various inflammatory diseases, including atherosclerosis, rheumatoid arthritis, and systemic lupus erythematosus. Elevated levels of CD40L are associated with cardiovascular events and autoimmune diseases.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAlternative names:\u003c\/strong\u003e CD40 ligand, CD40-L, CD40L, T-cell antigen Gp39, TNF-related activation protein, TRAP, Tumor necrosis factor ligand superfamily member 5, TNFSF5, CD154, hyper-IgM syndrome, HIGM1, T-B cell-activating molecule, T-BAM.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 18.3 kDa\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFormulation:\u003c\/strong\u003e Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% glycerol, 0.2M NaCl.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eConcentration: \u003c\/strong\u003e0.5mg\/mL\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt; 95% by SDS-PAGE\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e SDS-PAGE\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage Condition:\u003c\/strong\u003e Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 13px; font-weight: 700; text-transform: uppercase;\"\u003e\u003cstrong\u003eResearch use only.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/wp-content\/uploads\/2025\/02\/TBP0112-Recombinant-human-CD40LG_2025_DL.pdf\"\u003eDatasheet (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/wp-content\/uploads\/2025\/02\/TBP0112_Recombinant-human-CD40LG_MSDS.pdf\"\u003eMSDS (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003cp\u003e1. Somani, S., Menta, L., Wang-Johanning, F., Johanning, G., Hong, S., \u0026amp; Njoo, E. (2025, April 03). Synthesis, anticancer properties, and biological profiling of synthetic glycan analogs of proscillaridin A. bioRxiv. \u003ca href=\"https:\/\/doi.org\/10.1101\/2025.03.31.646140\"\u003ehttps:\/\/doi.org\/10.1101\/2025.03.31.646140\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e2. Somani, S., Menta, L., Wang-Johanning, F., Johanning, G., Hong, S., \u0026amp; Njoo, E. (2025, October 27). Synthesis, anticancer properties, and biological profiling of synthetic glycan analogs of proscillaridin A. \u003cem\u003eDiscover Pharmaceutical Sciences\u003c\/em\u003e. 1, 25 (2025). \u003ca href=\"https:\/\/doi.org\/10.1007\/s44395-025-00025-1\"\u003ehttps:\/\/doi.org\/10.1007\/s44395-025-00025-1\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e3. Gutti, M., Tsui, M., Yang, S., Xi, S., Luo, J., Desarkar, A., Xie, Y., Feng, M., Avadhani, U., Raghavan, S., Brierley-Green, E., Yu, E., \u0026amp; Njoo, E. (2025). Synthetic Derivatives of Vinpocetine as Antiproliferative Agents. \u003cem\u003eDrugs and Drug Candidates\u003c\/em\u003e, \u003cem\u003e4\u003c\/em\u003e(4), 53. \u003ca href=\"https:\/\/doi.org\/10.3390\/ddc4040053\" target=\"_blank\" rel=\"noopener\"\u003ehttps:\/\/doi.org\/10.3390\/ddc4040053\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 13px; font-weight: 700; text-transform: uppercase;\"\u003e\u003cstrong\u003eResearch use only.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"TriBioScience","offers":[{"title":"10 ug","offer_id":45986503721039,"sku":"TBP0112-10UG","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"20 ug","offer_id":45986503753807,"sku":"TBP0112-20UG","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"50 ug","offer_id":45986503786575,"sku":"TBP0112-50UG","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"100 ug","offer_id":45986503819343,"sku":"TBP0112-100UG","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/TBP0112.png?v=1782812734","url":"https:\/\/www.danyel.co.il\/products\/recombinant-human-cd40lg-protein-tbp0112-10ug","provider":"danyel biotech","version":"1.0","type":"link"}