{"product_id":"readytoprocess-mabselect-prisma-protein-a-columns-17549861","title":"ReadyToProcess™ MabSelect PrismA protein A columns","description":"\u003cp\u003eThese prepacked chromatography columns are filled with MabSelect PrismA protein A resin. The protein ligand is genetically engineered to allow for efficient resin cleaning. This together with enhanced dynamic binding capacity, provides improved economy in monoclonal antibody purification, including many bispecific antibodies.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEnhanced dynamic binding capacity allows high mass throughput of processed mAb per resin volume unit.\u003c\/li\u003e\n\u003cli\u003eExcellent alkaline stability enables efficient cleaning and sanitization using 0.5–1.0 M NaOH for improved process economy, bioburden control, and robustness.\u003c\/li\u003e\n\u003cli\u003eCovered by a comprehensive security of supply program, including dual sources of the high-flow agarose base matrix and protein A ligand.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe next-generation protein A resin is here\u003c\/p\u003e\n\n\u003cp\u003eReadyToProcess MabSelect PrismA chromatography columns build on the proven track record of ReadyToProcess MabSelect and MabSelect SuRe packed columns, ensuring the goals of tomorrow's bioprocess-scale mAb production are met. These protein A columns take dynamic binding capacity and ligand alkali stability to the next level, which ensures enhanced process economy in antibody capture.\u003c\/p\u003e\n\n\u003cp\u003eConvenience and versatility of ReadyToProcess chromatography columns\u003c\/p\u003e\n\n\u003cul\u003e\n\t\u003cli\u003eRobust design and validated column packing methods for consistent performance.\u003c\/li\u003e\n\t\u003cli\u003eStandardized format for reduced cost and column off-the-shelf availability for short delivery lead times.\u003c\/li\u003e\n\t\u003cli\u003eCost-saving by eliminating the need for column packing, preparation, and validation procedures.\u003c\/li\u003e\n\t\u003cli\u003eColumns fulfil industrial demands for security of supply, robust performance, and \u003ca href=\"\/support\/quality\/regulatory-support\"\u003eregulatory support\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eThe enhanced alkaline stability of MabSelect PrismA also provides opportunities for more robust mAb purification using periodic counter-current chromatography. The possibility for cleaning using 1 M NaOH increases bioburden control for continuous processes, which can be exposed to days or weeks of feed harvest.\u003c\/p\u003e\n\n\u003cp\u003eMabSelect PrismA builds on the proven track record of MabSelect and MabSelect SuRe resins in commercial monoclonal antibody and Fc-fusion protein purification.\u003c\/p\u003e\n\n\u003cp\u003eLearn about prepacked \u003ca href=\"\/shop\/chromatography\/resins\/affinity-antibody\/mabselect-prisma-protein-a-chromatography-resin-p-09659\"\u003eMabSelect PrismA\u003c\/a\u003e, \u003ca href=\"\/shop\/chromatography\/prepacked-columns\/affinity-antibody\/hiscreen-mabselect-prisma-protein-a-column-p-09649\"\u003eHiScreen MabSelect PrismA\u003c\/a\u003e, \u003ca href=\"\/shop\/chromatography\/prepacked-columns\/affinity-antibody\/hitrap-mabselect-prisma-protein-a-column-p-09656\"\u003eHiTrap MabSelect PrismA\u003c\/a\u003e, \u003ca href=\"\/shop\/chromatography\/prepacked-columns\/affinity-antibody\/predictor-mabselect-prisma-filter-plates-96-well-p-09651\"\u003ePreDictor MabSelect PrismA\u003c\/a\u003e or \u003ca href=\"\/shop\/chromatography\/prepacked-columns\/affinity-antibody\/predictor-robocolumn%E2%84%A2-mabselect-prisma-p-09660\"\u003ePreDictor Robocolumns MabSelect PrismA\u003c\/a\u003e\u003c\/p\u003e\n\n\u003cp\u003eLearn how Bispecific antibodies (BsAb) can be purified using \u003ca href=\"\/Solutions\/Bioprocessing\/Knowledge-center\/Purifying-bispecific-antibodies-in-a-single-step\"\u003eprotein A chromatography\u003c\/a\u003e in only a single step\u003c\/p\u003e\n\n\u003cp\u003eLearn about reducing \u003ca href=\"\/solutions\/bioprocessing\/knowledge-center\/Sanitization-of-protein-A-affinity-resins\"\u003ebioburden and sanitization of MabSelect PrismA\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-26546-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-18412-pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"150 mm \/ 80 mm \/ 0.8 L, Standard","offer_id":45982451269711,"sku":"29420989","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"150 mm \/ 359 mm \/ 15 L, Standard","offer_id":45982451302479,"sku":"29601750","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"200 mm \/ 80 mm \/ 1 L, Standard","offer_id":45982451335247,"sku":"17549861","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"200 mm \/ 126 mm \/ 2.5 L, Standard","offer_id":45982451368015,"sku":"17549862","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"200 mm \/ 178 mm \/ 5 L, Standard","offer_id":45982451400783,"sku":"17549863","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"200 mm \/ 251 mm \/ 10 L, Standard","offer_id":45982451433551,"sku":"17549864","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"200 mm \/ 359 mm \/ 20 L, Standard","offer_id":45982451466319,"sku":"17549865","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"200 mm \/ 450 mm \/ 32 L, Standard","offer_id":45982451499087,"sku":"17549866","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"200 mm \/ 600 mm \/ 57 L, Standard","offer_id":45982451531855,"sku":"17549867","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-26479-original-png.png?v=1782743236","url":"https:\/\/www.danyel.co.il\/products\/readytoprocess-mabselect-prisma-protein-a-columns-17549861","provider":"danyel biotech","version":"1.0","type":"link"}