{"product_id":"orgentec-anti-ndna-antibodies-ndna-ifa-kit-org-871","title":"Anti-nDNA Antibodies (nDNA) IFA Kit","description":"\u003cp\u003eIndirect immunofluorescence test for the qualitative determination of anti-nDNA IgG antibodies in serum or plasma.\u003c\/p\u003e\u003cp\u003eDetection of antibodies against native double-stranded DNA (Anti-nDNA, Anti-dsDNA) is very important for laboratory diagnostics of systemic lupus erythematosous (SLE). Immunofluorescence assays based on antigens of the flagellate Crithidia luciliae have a high diagnostic specificity. Sensitivity is somewhat lower, especially in patients with no signs for an active disease state.\u003c\/p\u003e\u003cp\u003eAntibodies against native DNA are more than specific markers for the disease; they are also suitable parameters for measuring lupus disease activity. Therefore, Anti-nDNA antibodies are among the most frequently detected autoantibodies that are associated with SLE. They are found in 95 % of SLE patients with renal involvement, in 50 – 70 % of SLE patients without renal involvement and in 40 % of patients with inactive SLE. Anti-nDNA antibodies are rarely found in healthy individuals.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eFormat: indirect immunofluorescence (IFA) slide kit.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eParameter\u003c\/th\u003e\n\u003cth\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eTests\u003c\/td\u003e\n\u003ctd\u003e120 (10 slides, 12 wells each)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCoating\u003c\/td\u003e\n\u003ctd\u003eCrithidia luciliae\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003ch2\u003eKit Components\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eComponent\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eSlides Anti-nDNA Antibodies (nDNA)\u003c\/td\u003e\n\u003ctd\u003eCrithidia luciliae – 10 slides x 12 wells\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003enDNA Positive Control\u003c\/td\u003e\n\u003ctd\u003eanti-nDNA antibodies (for Crithidia luciliae) – 0.3 ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIgG FITC\/Evans\u003c\/td\u003e\n\u003ctd\u003efor human cells and Crithidia luciliae – 3 ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMounting Medium\u003c\/td\u003e\n\u003ctd\u003emounting medium – 3 ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePBS (10x)\u003c\/td\u003e\n\u003ctd\u003ephosphate buffer saline (PBS 10x) – 100 ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNegative Control\u003c\/td\u003e\n\u003ctd\u003eNegative Control for IFA – 0.3 ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBlotting Paper 1 x 12\u003c\/td\u003e\n\u003ctd\u003efilter paper for 12 wells – 10 pcs.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/products.orgentec.com\/pdfs\/ifu\/ORG%20871_IFU_EN_QM122131_2026-06-30_3.pdf\" target=\"_blank\" rel=\"noopener\"\u003eInstruction for Use\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/products.orgentec.com\/pdfs\/sds\/ORG%20871.zip\" target=\"_blank\" rel=\"noopener\"\u003eSafety Data Sheet\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eInstruction for Use Revision 3. Earlier versions and additional languages can be found in the document archive.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eTests\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003eORG 871\u003c\/td\u003e\n\u003ctd\u003eAnti-nDNA Antibodies (nDNA)\u003c\/td\u003e\n\u003ctd\u003e120 (10 slides, 12 wells each)\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"ORGENTEC Diagnostika","offers":[{"title":"Default Title","offer_id":67630232862799,"sku":"ORG 871","price":0.0,"currency_code":"ILS","in_stock":true}],"url":"https:\/\/www.danyel.co.il\/products\/orgentec-anti-ndna-antibodies-ndna-ifa-kit-org-871","provider":"danyel biotech","version":"1.0","type":"link"}