{"product_id":"orgentec-anti-lc1-alegria-monotest-org-258","title":"Anti-LC1 Alegria Monotest","description":"\u003cp\u003eAnti-LC1 is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against liver cytosolic protein type 1 (LC1) in human serum or plasma. It is used to support the differential diagnosis of liver diseases, particularly in cases of suspected type 2 autoimmune hepatitis.\u003c\/p\u003e\u003cp\u003eThe detection of autoantibodies plays a central role in the diagnosis of inflammatory liver diseases namely autoimmune hepatitis (AIH), primary biliary cirrhosis and sclerosing cholangitis in adults and children. Anti-smooth muscle antibodies (ASMA), anti-nuclear antibodies (ANA), and antibodies against the soluble liver antigen (anti-SLA) define AIH type 1. Liver-kidney microsome antibodies (anti-LKM-1) and liver cytosolic protein type 1 antibodies (anti-LC1) may be present in AIH type 2.\u003c\/p\u003e\u003cp\u003eAnti-LC1 may be the single antibody in up to one third of the patients with AIH-2, and AIH-2 patients with anti-LC1 antibodies have histologically more severe disease compared to those without anti-LC1 antibodies.\u003c\/p\u003e\u003cp\u003eAnti-LC1 was originally described in association with anti-LKM-1, or in isolation in patients with AIH-2. Anti-LC1 antibodies have also been found in 14 % anti-LKM-1 antibody positive patients suffering from chronic hepatitis C virus infection.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eFormat: Alegria® Monotest strips for the fully automated Alegria® \/ Alegria® 2 analyzers.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eParameter\u003c\/th\u003e\n\u003cth\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eTests\u003c\/td\u003e\n\u003ctd\u003e24 Alegria strips\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCalibration\u003c\/td\u003e\n\u003ctd\u003einternal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCalculation\u003c\/td\u003e\n\u003ctd\u003equantitative\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRange\u003c\/td\u003e\n\u003ctd\u003e0 - 100 U\/ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCut-off\u003c\/td\u003e\n\u003ctd\u003e10 U\/ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCoating\u003c\/td\u003e\n\u003ctd\u003eLC1 (liver cytosolic protein type 1)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/products.orgentec.com\/pdfs\/ifu\/ORG%20258_IFU_EN_QM151532_2024-07-16_3.pdf\" target=\"_blank\" rel=\"noopener\"\u003eInstruction for Use\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/products.orgentec.com\/pdfs\/sds\/ORG%20258.zip\" target=\"_blank\" rel=\"noopener\"\u003eSafety Data Sheet\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eInstruction for Use Revision 3. Earlier versions and additional languages can be found in the document archive.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eTests\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003eORG 258\u003c\/td\u003e\n\u003ctd\u003eAnti-LC1\u003c\/td\u003e\n\u003ctd\u003e24 Alegria strips\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"ORGENTEC Diagnostika","offers":[{"title":"Default Title","offer_id":67630225358927,"sku":"ORG 258","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/proven_monotest.jpg?v=1791292017","url":"https:\/\/www.danyel.co.il\/products\/orgentec-anti-lc1-alegria-monotest-org-258","provider":"danyel biotech","version":"1.0","type":"link"}