{"product_id":"orgentec-anti-dgp-elisa-kit-org-551a","title":"Anti-DGP ELISA Kit","description":"\u003cp\u003eAnti-DGP IgA is an ELISA test for the quantitative determination of IgA and\/or IgG antibodies against deamidated gliadin peptide epitopes (DGP) in human serum or plasma. The assays Anti-DGP IgA, Anti-DGP IgG, and Anti-DGP Screen are used to support a diagnosis of celiac disease.\u003c\/p\u003e\u003cp\u003eAfter resorption, gliadin from food is deamidated by tissue transglutaminase (tTG) in the gastric mucosa. Gliadin fragments (deamidated gliadin peptides) bind to the HLA molecules of antigen-presenting cells. Once placed in context with specific HLA molecules, the fragments are recognized by corresponding T-helper cells. This results in an extensive immune response that includes formation of antibodies against tTG and DGP.\u003c\/p\u003e\u003cp\u003eIn serum samples from celiac patients, IgA and IgG antibodies against deamidated gliadin peptide epitopes are found. The IgA antibodies make it possible to determine the level of disease activity and to monitor adherence to a gluten-free diet. Because a substantial percentage of celiac patients are deficient in IgA antibodies, sensitive screening of individuals at risk always also includes testing for IgG antibodies. Anti-DGP Screen detects antibodies of both subclasses, IgA and IgG in a single test step, and thus also identifies celiac disease patients with IgA deficiency.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAnti-DGP IgA\u003c\/strong\u003e (Cat. no. ORG 551A)\u003c\/p\u003e\u003cp\u003eAnti-DGP IgA is an ELISA test for the quantitative determination of IgA and\/or IgG antibodies against deamidated gliadin peptide epitopes (DGP) in human serum or plasma. The assays Anti-DGP IgA, Anti-DGP IgG, and Anti-DGP Screen are used to support a diagnosis of celiac disease.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAnti-DGP IgG\u003c\/strong\u003e (Cat. no. ORG 551G)\u003c\/p\u003e\u003cp\u003eAnti-DGP IgG is an ELISA test for the quantitative determination of IgG antibodies against deamidated gliadin protein epitopes (DGP) in human serum or plasma. These assays are used to support a diagnosis of celiac disease.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eFormat: ELISA kit, 96-well microplate format.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eParameter\u003c\/th\u003e\n\u003cth\u003eIgA\u003c\/th\u003e\n\u003cth\u003eIgG\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eTests\u003c\/td\u003e\n\u003ctd\u003e12 x 8 tests\u003c\/td\u003e\n\u003ctd\u003e12 x 8 tests\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCalibration\u003c\/td\u003e\n\u003ctd\u003einternal\u003c\/td\u003e\n\u003ctd\u003einternal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCalculation\u003c\/td\u003e\n\u003ctd\u003equantitative\u003c\/td\u003e\n\u003ctd\u003equantitative\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRange\u003c\/td\u003e\n\u003ctd\u003e0 - 100 U\/ml\u003c\/td\u003e\n\u003ctd\u003e0 - 100 U\/ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCut-off\u003c\/td\u003e\n\u003ctd\u003e10 U\/ml\u003c\/td\u003e\n\u003ctd\u003e10 U\/ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCoating\u003c\/td\u003e\n\u003ctd\u003edeamidated gliadin proteins (DGP)\u003c\/td\u003e\n\u003ctd\u003edeamidated gliadin proteins (DGP)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eAlso available as Alegria Monotest (ORG 251A, ORG 251G, ORG 251S).\u003c\/p\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/products.orgentec.com\/pdfs\/ifu\/ORG%20551A_IFU_EN_QM113186_2024-07-19_4.pdf\" target=\"_blank\" rel=\"noopener\"\u003eInstruction for Use – ORG 551A\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/products.orgentec.com\/pdfs\/sds\/ORG%20551A.zip\" target=\"_blank\" rel=\"noopener\"\u003eSafety Data Sheet – ORG 551A\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/products.orgentec.com\/pdfs\/ifu\/ORG%20551G_IFU_EN_QM113187_2024-07-19_4.pdf\" target=\"_blank\" rel=\"noopener\"\u003eInstruction for Use – ORG 551G\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/products.orgentec.com\/pdfs\/sds\/ORG%20551G.zip\" target=\"_blank\" rel=\"noopener\"\u003eSafety Data Sheet – ORG 551G\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eInstruction for Use Revision 4. Earlier versions and additional languages can be found in the document archive.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eTests\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eORG 551A\u003c\/td\u003e\n\u003ctd\u003eAnti-DGP IgA\u003c\/td\u003e\n\u003ctd\u003e12 x 8 tests\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eORG 551G\u003c\/td\u003e\n\u003ctd\u003eAnti-DGP IgG\u003c\/td\u003e\n\u003ctd\u003e12 x 8 tests\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"ORGENTEC Diagnostika","offers":[{"title":"IgA","offer_id":67630212317263,"sku":"ORG 551A","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"IgG","offer_id":67630212350031,"sku":"ORG 551G","price":0.0,"currency_code":"ILS","in_stock":true}],"url":"https:\/\/www.danyel.co.il\/products\/orgentec-anti-dgp-elisa-kit-org-551a","provider":"danyel biotech","version":"1.0","type":"link"}