{"product_id":"orgentec-anti-centromere-b-elisa-kit-org-633","title":"Anti-Centromere B ELISA Kit","description":"\u003cp\u003eAnti-Centromere B is an ELISA test system for the quantitative determination of IgG antibodies against centromere B in human serum or plasma.\u003c\/p\u003e\u003cp\u003eThe detection of autoantibodies against centromere protein B is of great diagnostic and prognostic importance in cases of progressive systemic scleroderma (PSS).\u003c\/p\u003e\u003cp\u003eCentromere protein B is a DNA-associated protein. Together with other proteins, it forms the kinetochores of the chromosomes. Centromere B is the target antigen in over 95 % of patients with scleroderma or Raynaud’s phenomenon. Because autoantibodies against centromere proteins sometimes appear years before the disease appears, detection of anti-centromere B can be a significant indicator for the onset of scleroderma.\u003c\/p\u003e\u003cp\u003eCREST syndrome, a limited and localized form of scleroderma with a more favourable prognosis can be serologically detected at an early stage with use of the ORGENTEC Anti-Centromere B test.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eFormat: ELISA kit, 96-well microplate format.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eParameter\u003c\/th\u003e\n\u003cth\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eTests\u003c\/td\u003e\n\u003ctd\u003e12 x 8 tests\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCalibration\u003c\/td\u003e\n\u003ctd\u003einternal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCalculation\u003c\/td\u003e\n\u003ctd\u003equantitative\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRange\u003c\/td\u003e\n\u003ctd\u003e0 - 300 U\/ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCut-off\u003c\/td\u003e\n\u003ctd\u003e10 U\/ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCoating\u003c\/td\u003e\n\u003ctd\u003ecentromere B\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eAlso available as Alegria Monotest (ORG 200, ORG 233, ORG 238); ELISA Kit (ORG 538, ORG 539, ORG 600).\u003c\/p\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/products.orgentec.com\/pdfs\/ifu\/ORG%20633_IFU_EN_QM113209_2024-07-22_4.pdf\" target=\"_blank\" rel=\"noopener\"\u003eInstruction for Use\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/products.orgentec.com\/pdfs\/sds\/ORG%20633.zip\" target=\"_blank\" rel=\"noopener\"\u003eSafety Data Sheet\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eInstruction for Use Revision 4. Earlier versions and additional languages can be found in the document archive.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eTests\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003eORG 633\u003c\/td\u003e\n\u003ctd\u003eAnti-Centromere B\u003c\/td\u003e\n\u003ctd\u003e12 x 8 tests\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"ORGENTEC Diagnostika","offers":[{"title":"Default Title","offer_id":67630207631439,"sku":"ORG 633","price":0.0,"currency_code":"ILS","in_stock":true}],"url":"https:\/\/www.danyel.co.il\/products\/orgentec-anti-centromere-b-elisa-kit-org-633","provider":"danyel biotech","version":"1.0","type":"link"}