{"product_id":"mabselect-prisma-protein-a-chromatography-resin-17549803","title":"MabSelect PrismA™ protein A chromatography resin","description":"\u003cp\u003eMabSelect PrismA™ affinity chromatography resin has been improved with an optimized high-flow agarose base matrix and a genetically engineered protein A-derived ligand. This allows future demands in mAb purification to be met, including processing of many bispecific antibodies.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEnhanced dynamic binding capacity allows high mass throughput of processed mAb per resin volume unit.\u003c\/li\u003e\n\u003cli\u003eExcellent alkaline stability enables efficient cleaning and sanitization using 0.5–1.0 M NaOH for improved process economy, bioburden control, and robustness.\u003c\/li\u003e\n\u003cli\u003eCovered by a comprehensive security of supply program, including dual sources of the agarose base matrix and protein A ligand.\u003c\/li\u003e\n\u003cli\u003eThe PrismA protein A ligand is also available in HiTrap Fibro™ and HiScreen Fibro™ PrismA chromatography units for ultrafast purification of mAbs.\u003c\/li\u003e\n\u003cli\u003eEasily measure protein A leakage using the PrismA ELISA kit specifically designed for use with MabSelect PrismA™ resins.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe enhanced alkaline stability of MabSelect PrismA™ also provides opportunities for more robust mAb purification using periodic counter-current chromatography. The possibility for cleaning using 1 M NaOH increases bioburden control for continuous processes, which can be exposed to days or weeks of feed harvest.\u003c\/p\u003e\n\n\u003cp\u003eFor samples, contact your local sales representative or \u003ca href=\"\/support\/contact-us\"\u003ecustomer support.\u003c\/a\u003e\u003c\/p\u003e\n\n\u003cp\u003eMabSelect PrismA™ protein A resin builds on the proven track record of MabSelect™ and MabSelect SuRe™ resins in downstream processing of monoclonal antibodies.\u003c\/p\u003e\n\n\u003cp\u003eLearn about \u003ca href=\"\/shop\/chromatography\/prepacked-columns\/affinity-antibody\/readytoprocess-mabselect-prisma-protein-a-columns-p-09647\"\u003eReadyToProcess MabSelect PrismA™\u003c\/a\u003e, prepacked \u003ca href=\"\/shop\/chromatography\/prepacked-columns\/affinity-antibody\/hiscreen-mabselect-prisma-protein-a-column-p-09649\"\u003eHiScreen MabSelect PrismA™\u003c\/a\u003e, \u003ca href=\"\/shop\/chromatography\/prepacked-columns\/affinity-antibody\/hitrap-mabselect-prisma-protein-a-column-p-09656\"\u003eHiTrap MabSelect PrismA™\u003c\/a\u003e, \u003ca href=\"\/shop\/chromatography\/prepacked-columns\/affinity-antibody\/predictor-mabselect-prisma-filter-plates-96-well-p-09651\"\u003ePreDictor MabSelect PrismA™\u003c\/a\u003e or \u003ca href=\"\/shop\/chromatography\/prepacked-columns\/affinity-antibody\/predictor-robocolumn%E2%84%A2-mabselect-prisma-p-09660\"\u003ePreDictor Robocolumns MabSelect PrismA™\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003cp\u003eLearn how Bispecific antibodies (BsAb) can be purified using \u003ca href=\"\/Solutions\/Bioprocessing\/Knowledge-center\/Purifying-bispecific-antibodies-in-a-single-step\"\u003eprotein A chromatography\u003c\/a\u003e in only a single step.\u003c\/p\u003e\n\n\u003cp\u003eLearn about \u003ca href=\"\/solutions\/bioprocessing\/knowledge-center\/column-packing-for-mabselect-prisma-resin\"\u003elarge scale column packing using MabSelect PrismA™\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003cp\u003eLearn about reducing \u003ca href=\"\/solutions\/bioprocessing\/knowledge-center\/Sanitization-of-protein-A-affinity-resins\"\u003ebioburden and sanitization of MabSelect PrismA™\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-26546-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-29872-pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"1 L","offer_id":45982358831183,"sku":"17549803","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"5 L","offer_id":45982358863951,"sku":"17549804","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"10 L","offer_id":45982358896719,"sku":"17549805","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"25 mL","offer_id":45982358929487,"sku":"17549801","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"200 mL","offer_id":45982358962255,"sku":"17549802","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-26539-original-png_05a7ed01-f145-4bef-a734-c1c67dfd5451.png?v=1785960477","url":"https:\/\/www.danyel.co.il\/products\/mabselect-prisma-protein-a-chromatography-resin-17549803","provider":"danyel biotech","version":"1.0","type":"link"}