{"product_id":"lentil-lectin-sepharose-4b-resin-for-glycoprotein-purification-17044401","title":"Lentil Lectin Sepharose 4B resin for glycoprotein purification","description":"\u003cp\u003eLentil Lectin Sepharose 4B resin is used for glycoprotein purification and purification of other carbohydrate-containing molecules.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBinds molecules that contain α-D-mannose, α-D-glucose, and sterically related sugars.\u003c\/li\u003e\n\u003cli\u003eCompared to Con A, lentil lectin distinguishes less sharply between glucosyl and mannosyl residues.\u003c\/li\u003e\n\u003cli\u003eRetains binding in 1% deoxycholate and is valuable for purifying detergent-solubilized membrane proteins.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCapture of proteins with affinity for lentil lectin\u003c\/p\u003e \u003cp\u003eLentil lectin is a metalloprotein that binds reversibly to polysaccharides and glycoconjugates containing glucose or mannose type sugars. Lentil Lectin Sepharose 4B is a group-specific adsorbent that is well-suited to purifying membrane proteins and viral glycoproteins.\u003c\/p\u003e \u003cp\u003eSuccessful use in published research\u003c\/p\u003e \u003cp\u003eThis affinity resin is used in a variety of applications, including:\u003c\/p\u003e \u003cul\u003e     \u003cli\u003eIsolation of modified \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22167180\/\"\u003eHIV-1 envelope glycoproteins\u003c\/a\u003e to study effects on the CD4 binding site\u003c\/li\u003e     \u003cli\u003ePurification of \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1216909\/\"\u003enative and recombinant human dopamine beta-hydroxylase\u003c\/a\u003e expressed in Drosophila Schneider 2 cells for comparison studies.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-12727-pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"25 mL","offer_id":45982375313487,"sku":"17044401","price":4730.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/69c2a45ee6724ce6b5869640310fc044_c0068a0c-cd59-4882-b332-109d471ad662.png?v=1785956229","url":"https:\/\/www.danyel.co.il\/products\/lentil-lectin-sepharose-4b-resin-for-glycoprotein-purification-17044401","provider":"danyel biotech","version":"1.0","type":"link"}