{"product_id":"hydragel-von-willebrand-multimers-gel-electrophoresis-kit-4359","title":"HYDRAGEL von WILLEBRAND MULTIMERS Gel Electrophoresis Kit","description":"\u003cp\u003e\u003cstrong\u003eMultimer assay simplified.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003evon Willebrand disease (vWD) is a genetic bleeding disorder caused by missing or defective von Willebrand factor (vWF).\u003cbr\u003e Since von Willebrand disease (vWD) is a complex disease, its diagnosis requires a large panel of tests for an accurate diagnosis and classification of vWD. Multimer analysis is an integral part of the diagnostic process and an essential information for the clinicians for an optimal patient management.\u003c\/p\u003e \u003cp\u003eHYDRAGEL von WILLEBRAND MULTIMERS kit is designed for the detection of abnormalities in the vWF multimers distribution related to a haemorrhagic diathesis. The test allows to assess the overall size distribution of von Willebrand factor multimers in human plasma using agarose gel electrophoresis and immunofixation, with the semi-automated HYDRASYS 2 instrument.\u003c\/p\u003e\u003ch2\u003eKey Benefits\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSemi-automated test:\u003c\/strong\u003e providing standardised and reproducible results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSimplified technique:\u003c\/strong\u003e making this test accessible to any laboratory.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWithin-day results:\u003c\/strong\u003e compared to in house tests delivering results in 4-5 days.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTraceability of the result:\u003c\/strong\u003e with densitometry-based interpretations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eMain Characteristics\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eTest Principle\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eHYDRAGEL von WILLEBRAND MULTIMERS allows separating small, intermediate, and large molecular weight multimers.\u003c\/p\u003e \u003cp\u003eThe assay is carried out in two stages:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eSample pre-treatment followed by an electrophoresis done in SDS agarose gel to separate proteins according to their molecular weight,\u003c\/li\u003e \u003cli\u003edirect immunofixation of multimers in the gel using anti-human vWF antibody followed by immunoenzyme staining to visualize the different multimers.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThe semi-automated HYDRASYS 2 SCAN FOCUSING instrument performs all the steps needed to obtain gels ready for visual and densitometry-based interpretations.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSample Type\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003ePlasma samples\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePerformances\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e \u003cli\u003eExcellent reproducibility\u003c\/li\u003e \u003cli\u003eAll multimer sizes\u003c\/li\u003e \u003cli\u003eDensitometry helps for results interpretation\u003c\/li\u003e \u003cli\u003ePatient’s profile overlayed with a normal control\u003c\/li\u003e \u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. No.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eTests per gel\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e4359\u003c\/td\u003e\n\u003ctd\u003eHYDRAGEL 5 VON WILLEBRAND MULT\u003c\/td\u003e\n\u003ctd\u003e5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e4360\u003c\/td\u003e\n\u003ctd\u003eHYDRAGEL 11 VON WILLEBRAND MULT\u003c\/td\u003e\n\u003ctd\u003e11\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"Sebia","offers":[{"title":"5","offer_id":67629802094671,"sku":"4359","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"11","offer_id":67629802127439,"sku":"4360","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/zoom_gel_web_473x473_4a77dc63-6224-4249-b43f-a14bca1d52cc.png?v=1791291281","url":"https:\/\/www.danyel.co.il\/products\/hydragel-von-willebrand-multimers-gel-electrophoresis-kit-4359","provider":"danyel biotech","version":"1.0","type":"link"}