{"product_id":"hitrap-mabselect-prisma-protein-a-column-17549851","title":"HiTrap MabSelect PrismA™ protein A column","description":"\u003cp\u003eThese HiTrap columns are prepacked with MabSelect PrismA protein A chromatography resin. This affinity resin in the packed column has been improved with an optimized high-flow agarose base matrix and a genetically engineered protein ligand, allowing efficient cleaning between monoclonal antibody purification runs. This allows future demands in monoclonal antibody purification to be met, including processing of many bispecific antibodies.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEnhanced dynamic binding capacity compared with other protein A resins.\u003c\/li\u003e\n\u003cli\u003eExcellent alkaline stability enables efficient cleaning and sanitization using 0.5–1.0 M NaOH.\u003c\/li\u003e\n\u003cli\u003eConvenient HiTrap format for easy connection to a syringe, peristaltic pump, or chromatography systems such as an ÄKTA system for convenient process optimization.\u003c\/li\u003e\n\u003cli\u003eEasily measure protein A leakage using the PrismA ELISA kit specifically designed for use with MabSelect PrismA™ resins.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe enhanced alkaline stability of MabSelect PrismA also provides opportunities for more robust mAb purification using periodic counter-current chromatography. The possibility for cleaning using 1 M NaOH increases bioburden control for continuous processes, which can be exposed to days or weeks of feed harvest.\u003c\/p\u003e\n\u003cp\u003eMabSelect PrismA affinity chromatography resin builds on the proven track record of MabSelect and MabSelect SuRe protein A resins in commercial monoclonal antibody and Fc-fusion protein purification.\u003c\/p\u003e\n\u003cp\u003eLearn about \u003ca href=\"\/shop\/chromatography\/prepacked-columns\/affinity-antibody\/readytoprocess-mabselect-prisma-protein-a-columns-p-09647\"\u003eReadyToProcess MabSelect PrismA\u003c\/a\u003e, \u003ca href=\"\/shop\/chromatography\/resins\/affinity-antibody\/mabselect-prisma-protein-a-chromatography-resin-p-09659\"\u003eMabSelect PrismA\u003c\/a\u003e, prepacked \u003ca href=\"\/shop\/chromatography\/prepacked-columns\/affinity-antibody\/hitrap-mabselect-prisma-protein-a-column-p-09656\"\u003eHiTrap MabSelect PrismA\u003c\/a\u003e, \u003ca href=\"\/shop\/chromatography\/prepacked-columns\/affinity-antibody\/predictor-mabselect-prisma-filter-plates-96-well-p-09651\"\u003ePreDictor MabSelect PrismA\u003c\/a\u003e or \u003ca href=\"\/shop\/chromatography\/prepacked-columns\/affinity-antibody\/predictor-robocolumn%E2%84%A2-mabselect-prisma-p-09660\"\u003ePreDictor Robocolumns MabSelect PrismA\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-26546-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-26564-pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"1 × 1 mL","offer_id":45982416207951,"sku":"17549851","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"1 × 5 mL","offer_id":45982416240719,"sku":"17549853","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"5 × 1 mL","offer_id":45982416273487,"sku":"17549852","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"5 × 5 mL","offer_id":45982416306255,"sku":"17549854","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-26538-original-png_169c8540-dccb-4d91-9eaa-d7d0da92fe3e.png?v=1785960869","url":"https:\/\/www.danyel.co.il\/products\/hitrap-mabselect-prisma-protein-a-column-17549851","provider":"danyel biotech","version":"1.0","type":"link"}