{"product_id":"hemoglobin-e-hemoglobin-capillary-electrophoresis-kit-2507","title":"HEMOGLOBIN(E) Hemoglobin Capillary Electrophoresis Kit","description":"\u003cp\u003e\u003cstrong\u003eThe high-resolution method for hemoglobin disorders screening.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eHemoglobin electrophoresis is a well-established technique routinely used in clinical laboratories to screen patient samples for hemoglobinopathies (hemoglobin variants and thalassemias).\u003c\/p\u003e \u003cp\u003eMany international societies such as TIF, CDC and APHL recognise the benefits of the Sebia Capillary Electrophoresis (CE) technology, such as the high resolution and its clear hemoglobin fractions profile in the screening of hemoglobin disorders.\u003c\/p\u003e \u003cp\u003eIn addition to the Capillary electrophoresis, Sebia provides Gel technique-based solutions: HYDRAGEL HEMOGLOBIN(E) and HYDRAGEL ACID(E) HEMOGLOBIN(E) that enable, on the HYDRASYS instruments the separation of the hemoglobins and the detection of the major hemoglobin variants: S or D and C or E, by electrophoresis on alkaline agarose gels.\u003c\/p\u003e \u003cp\u003eElectrophoresis on acidic gels, like HYDRAGEL ACID(E) HEMOGLOBIN(E), should follow to confirm the identification of hemoglobin variants, mainly, to differentiate hemoglobins S from D and E from C.\u003c\/p\u003e \u003cp\u003eThe visualization of the gel provides qualitative and quantitative (HbA and HbA2) analysis.\u003c\/p\u003e\u003ch2\u003eKey Benefits\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFully automated:\u003c\/strong\u003e CAPILLARYS instruments perform all sequences automatically, from primary tube sampling to final clear-cut profile, with precise quantification and presumptive identification of the most common hemoglobins.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigh resolution:\u003c\/strong\u003e CAPILLARYS instruments allow high resolution separation of the major hemoglobin variants (Hb S, Hb C, Hb D and Hb E) and accurate quantification of the Hb A2 and Hb F. Furthermore, the Sebia CE technique is highly reproducible and the migration position given by the software can be used as an aid in the identification of Hb variants.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnhanced detection:\u003c\/strong\u003e Capillary zone electrophoresis allows clean separation of Hb E from Hb A2 and facilitates easier detection of Hb Bart’s and Hb H, the X-axis migration position is a great help in the presumptive identification of hemoglobin variants.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdapted to each laboratory:\u003c\/strong\u003e Thanks to the broad range of capillary instruments, the hemoglobin technique answers the needs and variable workload of all laboratories involved in abnormal hemoglobin screening.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eMain Characteristics\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eTest Principle\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e \u003cli\u003eThe HEMOGLOBIN(E) assay is based on the principle of capillary electrophoresis in free solution. Hemoglobin fractions are separated in silica capillaries, by their electrophoretic mobility and electroosmotic flow at a high voltage in an alkaline buffer.\u003c\/li\u003e \u003c\/ul\u003e \u003cul\u003e \u003cli\u003eHemoglobin fractions are directly detected at the specific absorbance of 415 nm. The pattern is divided into 15 zones (12 zones for cord blood). Each zone displays a drop-down library of possible variants migrating within this zone. More than 500 variants are listed.\u003c\/li\u003e \u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eSample Type\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eWhole blood sample are used and are analysed directly on Capillary instruments.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePerformances\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHEMOGLOBIN(E)\u003c\/strong\u003e\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eInstrument\u003c\/th\u003e\n\u003cth\u003eThroughput (tests\/hour)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAPILLARYS 3 OCTA\u003c\/td\u003e\n\u003ctd\u003e45\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAPILLARYS 3 TERA\u003c\/td\u003e\n\u003ctd\u003e65\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAPILLARYS 3 TERA MC3\u003c\/td\u003e\n\u003ctd\u003e176\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMINICAP FLEX-PIERCING\u003c\/td\u003e\n\u003ctd\u003e7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e* Using Software version 9.30\u003c\/p\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. No.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eInstrument\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e2507\u003c\/td\u003e\n\u003ctd\u003eCAPI 3 Hb\u003c\/td\u003e\n\u003ctd\u003eCAPILLARYS 3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e2207\u003c\/td\u003e\n\u003ctd\u003eMINICAP HEMOGLOBIN(E)\u003c\/td\u003e\n\u003ctd\u003eMINICAP FLEX-PIERCING\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"Sebia","offers":[{"title":"CAPILLARYS 3","offer_id":67629799243855,"sku":"2507","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"MINICAP FLEX-PIERCING","offer_id":67629799276623,"sku":"2207","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/OCTA_web.1.2.webp?v=1791284865","url":"https:\/\/www.danyel.co.il\/products\/hemoglobin-e-hemoglobin-capillary-electrophoresis-kit-2507","provider":"danyel biotech","version":"1.0","type":"link"}