{"product_id":"hedera-profiling-1-ctdna-test-panel-hp1-ctdna-t24-4lp126irm","title":"Hedera Profiling 1 ctDNA Test Panel (HP1 ctDNA), 115-Gene NGS Liquid Biopsy Kit, 24 Tests","description":"\u003cp\u003eHedera Profiling 1 ctDNA (HP1 ctDNA) brings the 115-gene HP1 design to liquid biopsy: a hybrid-capture NGS panel that detects SNVs, Indels, CNVs, Fusions, MSI and tumor fraction from plasma cfDNA in one DNA-only assay, covering all NCCN-guideline and ESCAT Level I targets. 24 tests per kit.\u003c\/p\u003e\u003cp\u003eKits are commercialized together with the Hedera Prime software and can be purchased separately.\u003c\/p\u003e\u003ch2\u003eKey Features\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompact but comprehensive:\u003c\/strong\u003e 115-gene panel for the detection of SNVs, Indels, CNVs, Fusions and MSI across all tumor types in a single, DNA-only assay\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHighly actionable:\u003c\/strong\u003e Covers all NCCN-guideline and ESCAT Level I genomic targets in solid tumors\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFast and accurate:\u003c\/strong\u003e Swiftly integrates into your routine NGS workflow to get accurate results with low input material within 5 calendar days\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRobust software analysis:\u003c\/strong\u003e Backed by Hedera Prime software, it saves time on each report while ensuring accurate and reliable results\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnique fusions detection method on DNA:\u003c\/strong\u003e Cutting-edge proprietary technology to detect fusions with unmatched precision, enhancing the accuracy of complex variants detection\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eWorkflow\u003c\/h2\u003e\u003cp\u003eThe kit integrates into your existing NGS workflow and sequencing instrument; tertiary analysis and reporting run in the Hedera Prime software.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e3 hours\u003c\/strong\u003e - hands on time\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e5 calendar days\u003c\/strong\u003e - from sample to report\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u0026lt; 5 minutes\u003c\/strong\u003e - tertiary analysis \u0026amp; reporting\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cimg src=\"https:\/\/cdn.prod.website-files.com\/651c4a232949c9f38286a491\/69ddd7d2a76dee08b683a9c4_HP1-workflow.png\" alt=\"Hedera Profiling 1 test panels sample-to-report workflow\" style=\"max-width:100%;height:auto\" loading=\"lazy\"\u003e\u003c\/p\u003e\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003ePanel size\u003c\/td\u003e\n\u003ctd\u003e297.6 kb\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNumber of genes\u003c\/td\u003e\n\u003ctd\u003e115 (79 full CDS)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReactions per kit\u003c\/td\u003e\n\u003ctd\u003e24 (6 captures of 4 samples)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInstruments supported\u003c\/td\u003e\n\u003ctd\u003eIllumina NextSeq and NovaSeq Series; Element Biosciences AVITI Systems\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRecommended input amount\u003c\/td\u003e\n\u003ctd\u003emin 10 ng (30 ng recommended)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLibrary enrichment method\u003c\/td\u003e\n\u003ctd\u003eHybrid-capture chemistry\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eUMI\/UDI technologies\u003c\/td\u003e\n\u003ctd\u003eallows error correction and prevents index hopping for enhanced sensitivity and specificity\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\u003ch2\u003eGene List\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eTumor types:\u003c\/strong\u003e Lung Cancer, Colorectal Cancer, Melanoma, Thyroid Cancer, Gastrointestinal Stromal Tumors (GIST), Cholangiocarcinoma and other solid tumors.\u003c\/p\u003e\u003cp\u003eAKT1, ALK, APC, AR, ARAF, AR Enhancer, ARID1A, ARID1B, ATM, ATR, ATRX, BARD1, BRAF, BRCA1, BRCA2, BRIP1, CCND1, CCNE1, CD274, CDK12, CDK4, CDKN2A, CDKN2B, CHEK1, CHEK2, CIC, CLDN18, CTNNB1, CUL3, DDR2, DICER1, EGFR, EPCAM, ERBB2, ERBB3, ERBB4, ERCC2, ESR1, FANCA, FANCL, FAT1, FBXW7, FGFR1, FGFR2, FGFR2b, FGFR3, FGFR4, FOXL2, GNA11, GNAQ, GNAS, H3-3A, H3-3B, HIST1H3B, HIST1H3C, HIST1H3H, HRAS, IDH1, IDH2, KEAP1, KIT, KLF4, KRAS, MAP2K1, MAP2K2, MDM2, MEN1, MET, MLH1, MRE11, MSH2, MSH6, MTAP, MTOR, MYC, NBN, NF1, NFE2L2, NOTCH1, NRAS, NTRK1, NTRK2, NTRK3, PALB2, PDCD1, PDGFRA, PIK3CA, PIK3R1, PMS2, POLD1, POLE, PPARG, PPP2R1A, PPP2R2A, PTCH1, PTEN, PTPN11, RAD51B, RAD51C, RAD51D, RAD54L, RAF1, RB1, RET, ROS1, SMAD4, SMARCA4, SMARCB1, SMO, STK11, TACSTD2, TERT Promoter, TP53, TRAF7, TSC1, TSC2, VHL\u003c\/p\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eSKU\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eFormat\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003eT24-4LP126IRM\u003c\/td\u003e\n\u003ctd\u003eHedera Profiling 1 ctDNA Test Panel (HP1 ctDNA)\u003c\/td\u003e\n\u003ctd\u003e24 tests\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003cem\u003eFor Research Use Only. Not for use in diagnostic procedures. This product is intended for laboratory research purposes only and is not intended for use in the diagnosis, prevention, monitoring, treatment, or alleviation of disease. This product has not been cleared or approved by any regulatory authority for clinical or diagnostic use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Hedera Dx","offers":[{"title":"Default Title","offer_id":46798498070607,"sku":"T24-4LP126IRM","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/69dccb89f2c93665cb1fdb6d_HP1-box-1x.png?v=1789655454","url":"https:\/\/www.danyel.co.il\/products\/hedera-profiling-1-ctdna-test-panel-hp1-ctdna-t24-4lp126irm","provider":"danyel biotech","version":"1.0","type":"link"}