{"product_id":"creb-dominant-negative-vector-set-631925","title":"CREB Dominant-Negative Vector Set","description":"\u003cp\u003eSet of three vectors for studying CREB-related signaling pathways. The pCMV-CREB Vector expresses the wild-type CREB protein. pCMVCREB133 Vector encodes a mutated form of CREB, blocking cAMP-induced transcription and preventing CREB phosphorylation. pCMVKCREB also encodes a mutated form of CREB, blocking cAMP-induced transcription. Each gene is expressed from the constitutive CMV promoter.\u003c\/p\u003e\n\u003ch2\u003eFeatures\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSimplify the complexities of signal transduction in vivo\u003c\/li\u003e\n\u003cli\u003eDissect the network of signal transduction pathways\u003c\/li\u003e\n\u003cli\u003eScreen for compounds that activate key pathways\u003c\/li\u003e\n\u003cli\u003eCombine with cis reporter vectors to create a complete assay system\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplications\u003c\/h2\u003e\n\u003cp\u003eMeasure and quantify signal transduction pathway activity\u003cbr\u003eActivation and knockdown studies\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.takarabio.com\/documents\/Certificate%20of%20Analysis\/631925\/631925-PA4Z086.pdf\"\u003eCertificate of Analysis (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.takarabio.com\/documents\/SDS\/S2329\/S2329-EGHS-EN.pdf\"\u003eSafety Data Sheet (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.takarabio.com\/documents\/Vector%20Documents\/PT3457-5.pdf\"\u003eCREB Dominant Negative Vector Set vector information\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.takarabio.com\/documents\/Vector%20Documents\/pCMV-CREB.gb\"\u003epCMV-CREB  vector sequence in GenBank format\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.takarabio.com\/documents\/Vector%20Documents\/pCMV-CREB133.gb\"\u003epCMV-CREB133  vector sequence in GenBank format\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.takarabio.com\/documents\/Vector%20Documents\/pCMV-KCREB.gb\"\u003epCMV-KCREB  vector sequence in GenBank format\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Takara Bio","offers":[{"title":"Each","offer_id":45986030452815,"sku":"631925","price":4562.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/631925-CREB-Dominant-Negative-Vector-Set-product-600.jpg?v=1782805569","url":"https:\/\/www.danyel.co.il\/products\/creb-dominant-negative-vector-set-631925","provider":"danyel biotech","version":"1.0","type":"link"}