{"product_id":"con-a-sepharose-4b-17044001","title":"Con A Sepharose™ 4B","description":"\u003cp\u003eCon A Sepharose 4B with immobilized Concanavalin A is an affinity chromatography resin for capture of glycosylated biomolecules including glycoproteins and glycolipids. Stronger affinity for α-D-glucose than α-D-mannose\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eConcanavalin A (Con A) binds molecules that contain α-D-mannose, α-D-glucose, and sterically related residues with available C-3, C-4, or C-5 hydroxyl groups\u003c\/li\u003e\n\u003cli\u003eGroup-specific adsorbent for molecules containing sugars.\u003c\/li\u003e\n\u003cli\u003eHighly suitable for isolation of cell surface glycoproteins from detergent-solubilized membranes\u003c\/li\u003e\n\u003cli\u003eConcanavalin A (Con A) binds molecules that contain α-D-mannose, α-D-glucose and sterically related residues with available C-3, C-4, or C-5 hydroxyl groups\u003c\/li\u003e\n\u003cli\u003eHighly suitable for isolation of cell surface glycoproteins from detergent-solubilized membranes\u003c\/li\u003e\n\u003cli\u003eCon A coupled to Sepharose 4B via cyanogen bromide activation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCon A Sepharose is Concanavalin A coupled to Sepharose 4B by the cyanogen bromide method. Concanavalin A (Con A) is a tetrameric metalloprotein isolated from \u003ci\u003eCanavalia ensiformis\u003c\/i\u003e (jack bean). Con A binds molcules containing α-D-mannopyranosyl, α-D-glucopyranosyl and sterically related residues. The binding sugar requires the presence of C-3, C-4 and C-5 hydroxyl groups for reaction with Con A. Con A coupled to Sepharose is routinely used for separation and purification of glycoproteins, polysaccharides and glycolipids\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-14393-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-49110-pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"5 mL","offer_id":45982377869391,"sku":"17044003","price":526.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL","offer_id":45982377902159,"sku":"17044001","price":5427.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/69c2a45ee6724ce6b5869640310fc044_c0068a0c-cd59-4882-b332-109d471ad662.png?v=1785956229","url":"https:\/\/www.danyel.co.il\/products\/con-a-sepharose-4b-17044001","provider":"danyel biotech","version":"1.0","type":"link"}