{"product_id":"cellartis-2i-mes-ipsc-culture-medium-y40031","title":"Cellartis® 2i mES\/iPSC Culture Medium","description":"\u003cp\u003eCellartis 2i mES\/iPSC Culture Medium is a serum-free, defined cell culture medium for the establishment of mouse ES and iPS cell lines. This medium contains two selective small molecule inhibitors ('2i'), CHIR99021 and PD0325901, that act to eliminate differentiation-inducing signals from GSK3β and ERK\/MEK, respectively, and promote cell proliferation.\u003c\/p\u003e\n\u003ch2\u003eFeatures\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCompletely defined, serum-free formulation promotes cell proliferation and maintains pluripotent state\u003c\/li\u003e\n\u003cli\u003eUses selective small molecule inhibitors to block differentiation signals from GSK3β and ERK\/MEK, allowing establishment and long-term maintenance of germline-competent mouse ES and iPS cells\u003c\/li\u003e\n\u003cli\u003eCan be combined with Leukemia Inhibitory Factor (LIF) to induce the efficient conversion of partial- or pre-iPS mouse cells into fully pluripotent iPS cells\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplications\u003c\/h2\u003e\n\u003cp\u003eEstablishment of mouse ES and iPS cell lines\u003c\/p\u003e\u003cp\u003eLong-term maintenance of pure ES or iPS cells\u003c\/p\u003e\u003cp\u003eConversion of partial- or pre-iPS cells into fully pluripotent cells in the presence of LIF\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.takarabio.com\/documents\/SDS\/SD7356\/SD7356-EGHS-EN.pdf\"\u003eSafety Data Sheet (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.takarabio.com\/documents\/User%20Manual\/Y40031\/Y40031_e.v2002.pdf\"\u003eUser Manual (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.takarabio.com\/documents\/Components%20List\/Y40031_v201912w_COA.pdf\"\u003eCellartis 2i mES\/iPSC Culture Medium Components List\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Takara Bio","offers":[{"title":"200 mL","offer_id":45986332311631,"sku":"Y40031","price":1845.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/Y40031-Cellartis-2i-mES-iPSC-Culture-Medium-product-600.jpg?v=1782808746","url":"https:\/\/www.danyel.co.il\/products\/cellartis-2i-mes-ipsc-culture-medium-y40031","provider":"danyel biotech","version":"1.0","type":"link"}