{"product_id":"cdt-carbohydrate-deficient-transferrin-capillary-electrophoresis-kit-2509","title":"CDT Carbohydrate-Deficient Transferrin Capillary Electrophoresis Kit","description":"\u003cp\u003e\u003cstrong\u003eThe most reliable chronic alcohol abuse marker.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eExcessive chronic alcohol consumption is a public health problem. Its diagnosis and monitoring will improve clinical outcome, reduce accidents and costs related to alcohol. Carbohydrate Deficient Transferrin (CDT) is the IFCC recommended biomarker for chronic alcohol abuse. CAPI 3 CDT and MINICAP CDT are designed to quantify CDT by capillary electrophoresis on patient serum samples. During analysis, serum transferrin isoforms are separated into five major fractions according to their sialylation level:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eAsialotransferrin (non-sialylated)\u003c\/li\u003e \u003cli\u003eDisialotransferrin\u003c\/li\u003e \u003cli\u003eTrisialotransferrin\u003c\/li\u003e \u003cli\u003eTetrasialotransferrin\u003c\/li\u003e \u003cli\u003ePentasialotranferrin\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eCDT\u003csub\u003eIFCC\u003c\/sub\u003e percent value is automatically displayed based on the calibration curve of disialotransferrin.\u003c\/p\u003e \u003cp\u003eIf CDT\u003csub\u003eIFCC\u003c\/sub\u003e is not implemented, a classic CDT percent value is automatically calculated using the low-sialylated isoforms, i.e., disialotransferrin associated with asialotransferrin (if present).\u003c\/p\u003e \u003cp\u003eThe interpretation is simple. CDT\u003csub\u003eIFCC\u003c\/sub\u003e greater than 2% are abnormal and indicative of chronic alcohol abuse whereas with classic CDT, results over 1.6%. are abnormal and indicative of chronic alcohol abuse.\u003c\/p\u003e\u003ch2\u003eKey Benefits\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSimple, secured and accurate CDT measurement:\u003c\/strong\u003e Normal clinical result: CDT IFCC ≤ 1.7% Forensic positive result: CDT IFCC \u0026gt; 2%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReduced hands-on time:\u003c\/strong\u003e Ready to use reagents, no sample pre-treatment and no need for additional total transferrin measurement.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAutomatic measurement with visualization of all transferrin isoforms:\u003c\/strong\u003e Potential analytical and genetical interferences (variants, CDG) and curve abnormalities (such as in cirrhotic pattern) can thus be detected and prevent false result reporting.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eScalable solution to fit all lab’s configuration:\u003c\/strong\u003e CDT is available on MINICAP and CAPILLARYS family offering multiple configurations for streamlined workflow.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eMain Characteristics\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eTest Principle\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e \u003cli\u003eCAPI 3 CDT – MINICAP CDT assays are based on the principle of capillary electrophoresis in free solution. Transferrin isoforms are separated in silica capillaries by their electrophoretic mobility and the electroosmotic flow at high voltage in an alkaline buffer. Transferrin isoforms are directly detected during migration by UV absorbance.\u003c\/li\u003e \u003c\/ul\u003e \u003cul\u003e \u003cli\u003eAll analysis steps are performed automatically. The sample dilution is done using a specific diluent allowing iron saturation.\u003c\/li\u003e \u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eSample Type\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eSerum sample is needed to perform CDT test. In the context of forensic use, the serum sample unlike hair and urine, can ensure the integrity, the reliability of the analysis and avoid possible fraud.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePerformances\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCDT\u003c\/strong\u003e\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eInstrument\u003c\/th\u003e\n\u003cth\u003eThroughput (tests\/hour)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAPILLARYS 3 OCTA\u003c\/td\u003e\n\u003ctd\u003e49\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAPILLARYS 3 TERA\u003c\/td\u003e\n\u003ctd\u003e73\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCAPILLARYS 3 TERA MC3\u003c\/td\u003e\n\u003ctd\u003e179\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMINICAP FLEX-PIERCING\u003c\/td\u003e\n\u003ctd\u003e10\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e* Using Software version 9.30\u003c\/p\u003e\u003cul\u003e \u003cli\u003eFull traceability and positive ID for samples and reagents\u003c\/li\u003e \u003cli\u003eRapid validation through color-coded profiles using the mosaic screen\u003c\/li\u003e \u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. No.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eInstrument\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e2509\u003c\/td\u003e\n\u003ctd\u003eCAPI 3 CDT\u003c\/td\u003e\n\u003ctd\u003eCAPILLARYS 3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e2208\u003c\/td\u003e\n\u003ctd\u003eMINICAP CDT\u003c\/td\u003e\n\u003ctd\u003eMINICAP FLEX-PIERCING\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"Sebia","offers":[{"title":"CAPILLARYS 3","offer_id":67629799637071,"sku":"2509","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"MINICAP FLEX-PIERCING","offer_id":67629799669839,"sku":"2208","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/OCTA_web.1.2.webp?v=1791284865","url":"https:\/\/www.danyel.co.il\/products\/cdt-carbohydrate-deficient-transferrin-capillary-electrophoresis-kit-2509","provider":"danyel biotech","version":"1.0","type":"link"}