{"product_id":"cd38-hydrolase-activity-fluorometric-assay-tbs2047","title":"CD38 hydrolase Activity Fluorometric Assay","description":"\u003cp\u003eCluster of Differentiation 38 (CD38) is a multifunctional ectoenzyme expressed in many immune cells including CD4\u003csup\u003e+\u003c\/sup\u003e, CD8\u003csup\u003e+\u003c\/sup\u003e, B lymphocytes, and natural killer cells. CD38 serves as a hydrolase and a nicotinamide adenine dinucleotide (NAD+) cyclase, involved in the metabolism of nicotinamide adenine dinucleotide (NAD\u003csup\u003e+\u003c\/sup\u003e) and nicotinamide adenine dinucleotide phosphate (NADP). The results are the production of Ca2\u003csup\u003e+\u003c\/sup\u003e-mobilizing compounds, such as cyclic ADP ribose (cADPR) and ADP ribose (ADPR). CD38 is used as a marker for poor prognosis in chronic lymphocytic leukemia and multiple myeloma and is an attractive cancer immunotherapy drug target.\u003c\/p\u003e\n\u003cp\u003eTribioscience’s CD38 hydrolase Assay Kit is a simple and fast fluorometric assay that measures the hydrolase activity of CD38 in biological samples. CD38 catalyzes the conversion of substrate to a florescent product which can be measured by fluorometric method at Ex\/Em=300 nm\/410 nm.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003eApplications\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMeasure CD38 hydrolase activity in a variety of samples.\u003c\/li\u003e\n\u003cli\u003eScreen CD38 hydrolase inhibitors.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003eStorage Conditions\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eStore the Reagent at -20°C, protect it from light. Shelf life: 12 months.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003eStandard Curve\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg class=\"alignnone wp-image-25989 lazyloaded\" src=\"https:\/\/tribioscience.com\/wp-content\/uploads\/2024\/03\/TBS2047-2.png\" alt=\"\" width=\"417\" height=\"297\" data-was-processed=\"true\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003c!--TBS2047--\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 13px; font-weight: 700; text-transform: uppercase;\"\u003e\u003cstrong\u003eResearch use only.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/wp-content\/uploads\/2024\/03\/TBS2047_CD38_hydrolase_Fluorometric_assay_datasheet_v03-2024.pdf\"\u003eDatasheet (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/wp-content\/uploads\/2024\/03\/TBS2047-CD38-hydrolase-Activity-Fluorometric-Assay_MSDS_2024.pdf\"\u003eMSDS (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"TriBioScience","offers":[{"title":"Default Title","offer_id":45986443493455,"sku":"TBS2047","price":2231.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/TBS2047.jpg?v=1782811099","url":"https:\/\/www.danyel.co.il\/products\/cd38-hydrolase-activity-fluorometric-assay-tbs2047","provider":"danyel biotech","version":"1.0","type":"link"}