{"product_id":"caspase-family-fluorometric-assay-kit-tbs2055","title":"Caspase-Family Fluorometric Assay Kit","description":"\u003cp\u003eApoptosis plays a fundamental role in many normal biological processes as well as in several disease states. Apoptosis can be induced by various stimuli that all produce the same end result: systematic and orderly cell death. The inflammasome is a large multiprotein complex whose assembly leads to the activation of caspase-1, which promotes the maturation of proinflammatory cytokines interleukin-1β (IL-1β) and IL-18. The Tribo™ CaspaseFamily fluorometric Assay Kits provide a simple and convenient means for assaying the activity of caspases family members (caspase-1, 2, 3, 4, 5, 6, 8, 9 \u0026amp;10). The assay is based on the detection of the free AFC fluorescence after cleavage from the labeled substrate. The free AFC can be quantified using a fluorometer or a fluorescence microtiter plate reader at Ex400\/Em505nm. Comparison of the fluorescence of AFC from an apoptotic sample with an uninduced control allows the determination of the fold increase in caspase-family member activity.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003eStorage Conditions\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eStore Cell Lysis buffer and Assay buffer at 4℃, Store all other components at -20℃. Shelf life of six months.\u003c\/p\u003e\n\u003cp\u003e\u003c!--TBS2055--\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 13px; font-weight: 700; text-transform: uppercase;\"\u003e\u003cstrong\u003eResearch use only.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/wp-content\/uploads\/2021\/01\/TBS2055_Caspase-Family_Fluorometric_assay_kit-1.pdf\"\u003eDatasheet (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/wp-content\/uploads\/2019\/04\/TBS2055-Caspase-Family_Fluorometric_assay_kit_MSDS_2024-1.pdf\"\u003eMSDS (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"TriBioScience","offers":[{"title":"Default Title","offer_id":45986443755599,"sku":"TBS2055","price":2683.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/TBS2055.png?v=1782811106","url":"https:\/\/www.danyel.co.il\/products\/caspase-family-fluorometric-assay-kit-tbs2055","provider":"danyel biotech","version":"1.0","type":"link"}