{"product_id":"caspase-1-fluorometric-assay-kit-tbs2045","title":"Caspase-1 Fluorometric Assay Kit","description":"\u003cp\u003eCaspase-1 (IL-1β Converting Enzyme, ICE) is the prototypical member of the ICE family of cysteine proteases, also known as caspases (cysteinyl aspartate-specific proteases). Caspase-1 was first identified as a novel protease that generates the proinflammatory cytokine, interleukin-1β by cleaving pro-interleukin-1β. It plays an important role in inflammatory diseases and cancer.\u003c\/p\u003e\n\u003cp\u003eTribo\u003csup\u003eTM\u003c\/sup\u003e Caspase-1 Activity Fluorometric Assay Kit provides a simple and convenient method for assaying the activity of caspases that recognize the sequence YVAD. The assay is based on the detection of the free AFC fluorescence after cleavage from the labeled substrate YVAD-AFC. The free AFC can be quantified using a fluorometer or a fluorescence microtiter plate reader at Ex400\/Em505nm. Comparison of the fluorescence of AFC from an apoptotic sample with an uninduced control allows the determination of the fold increase in caspase-1 activity.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003eRelated Products\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/product\/life-sciences\/biochemical-assays\/resazurin-cell-viability-kit\/\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eResazurin Cell Viability Assay (TBS2001)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/product\/life-sciences\/biochemical-assays\/ldh-cytotoxicity-assay\/\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eLDH Cytotoxicity Colorimetric Assay (TBS2002)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/product\/life-sciences\/biochemical-assays\/atp-colorimetric-fluorometric-assay-kit\/\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eATP Colorimetric\/Fluorometric Assay (TBS2010)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/product\/life-sciences\/biochemical-assays\/adp-colorimetric-fluorometric-assay-kit\/\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eADP Colorimetric\/Fluorometric Assay\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/product\/life-sciences\/biochemical-assays\/protein-assay-kit\/\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eProtein Assay (TBS2005)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003c!--TBS2045--\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 13px; font-weight: 700; text-transform: uppercase;\"\u003e\u003cstrong\u003eResearch use only.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/wp-content\/uploads\/2019\/04\/TBS2045_Caspase1_FL_Assay_V02-2023.pdf\"\u003eDatasheet (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/wp-content\/uploads\/2019\/04\/TBS2045-Caspase1_FL_Assay_MSDS_2024-1.pdf\"\u003eMSDS (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"TriBioScience","offers":[{"title":"Default Title","offer_id":45986443427919,"sku":"TBS2045","price":1317.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/TBS2045.jpg?v=1782811096","url":"https:\/\/www.danyel.co.il\/products\/caspase-1-fluorometric-assay-kit-tbs2045","provider":"danyel biotech","version":"1.0","type":"link"}