{"product_id":"capto-mmc-impres-multimodal-chromatography-resin-17371603","title":"Capto™ MMC ImpRes multimodal chromatography resin","description":"\u003cp\u003eDesigned for modern, large-scale manufacturers, this resin is used for high-resolution polishing of monoclonal antibodies (mAbs) and other biomolecules.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHigh yields achieved through the high-resolution beads and selectivity of the ligand.\u003c\/li\u003e\n\u003cli\u003eEfficient removal of aggregates, viruses, and main contaminants in mAb processes.\u003c\/li\u003e\n\u003cli\u003eEnables use of a platform approach to mAb process development.\u003c\/li\u003e\n\u003cli\u003eDisplays a broad operational window for pH and salt.\u003c\/li\u003e\n\u003cli\u003eSuitable for polishing of antibody fragments.\u003c\/li\u003e\n\u003cli\u003eResin fulfills industrial demands for security of supply, robust performance, and regulatory support.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSolve challenging purification problems\u003c\/p\u003e\n\n\u003cp\u003eThe weak cation exchange multimodal ligand enables high selectivity in a broad pH and salt window compared with traditional ion exchangers. This selectivity allows the use of Capto MMC ImpRes in a variety of process conditions to solve challenging purification problems.\u003c\/p\u003e\n\n\u003cp\u003eWide operation window for simplified processing\u003c\/p\u003e\n\n\u003cp\u003eThe multimodal cation exchanger ligand of Capto MMC ImpRes interacts with the target molecule through multiple types of interactions, including hydrogen bonding and hydrophobic interactions.\u003c\/p\u003e\n\n\u003cp\u003eCapto MMC ImpRes can be used for initial or final polishing steps in mAb purification processes. It can also be used for polishing of antibody fragments such as domain antibodies (DAbs).\u003c\/p\u003e\n\n\u003cp\u003eThe wide window of operation for conductivity and\/or pH simplifies the downstream process, because conditioning after the protein A step can be omitted. When working with sensitive mAbs, the wide window of operation simplifies optimization of conditions.\u003c\/p\u003e\n\n\u003cp\u003ePrepacked columns and other formats\u003c\/p\u003e\n\n\u003cp\u003eCapto MMC ImpRes resin is available in the following formats: \u003c\/p\u003e\n\n\u003cp\u003eProcess Development scale: prepacked\u003c\/p\u003e\n\n\u003cul\u003e\n\t\u003cli\u003e\n\u003ca href=\"\/shop\/chromatography\/prepacked-columns\/multimodal\/predictor-capto-mmc-impres-p-00467\"\u003ePreDictor Capto MMC ImpRes filter plates\u003c\/a\u003e, 96-well plates for high-throughput screening or process development.\u003c\/li\u003e\n\t\u003cli\u003e\n\u003ca href=\"\/shop\/chromatography\/prepacked-columns\/multimodal\/predictor-robocolumn-capto-mmc-impres-p-00496\"\u003ePreDictor MMC ImpRes RoboColumn™ units\u003c\/a\u003e, miniaturized columns for high-throughput process development.\u003c\/li\u003e\n\t\u003cli\u003e\n\u003ca href=\"\/shop\/chromatography\/prepacked-columns\/multimodal\/hiscreen-capto-mmc-impres-p-00495\"\u003eHiScreen Capto MMC ImpRes columns\u003c\/a\u003e, optimized for method and process development.\u003c\/li\u003e\n\t\u003cli\u003e\n\u003ca href=\"\/shop\/chromatography\/prepacked-columns\/hydrophobic-interaction\/f-x-columns-for-mechanistic-modeling-of-chromatography-p-25416\"\u003e\u003cem\u003ef\u003c\/em\u003e(x) column\u003c\/a\u003e, prepacked and precharacterized chromatography column for fast and accurate mechanistic modeling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eLab scale: prepacked for manual purification\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"\/shop\/chromatography\/prepacked-columns\/multimodal\/hitrap-capto-mmc-impres-p-00584\"\u003eHiTrap Capto MMC ImpRes columns\u003c\/a\u003e, for easy use with a syringe, peristaltic pump, or chromatography system.\u003c\/p\u003e\n\n\u003cp\u003eLab scale: prepacked for automated purification and analysis\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"\/shop\/chromatography\/prepacked-columns\/multimodal\/hitrap-capto-mmc-impres-p-00584\"\u003eHiTrap Capto MMC ImpRes columns\u003c\/a\u003e, for easy use with a syringe, peristaltic pump, or chromatography system.\u003c\/p\u003e\n\n\u003cp\u003eProcess characterization: resin kits\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"\/shop\/chromatography\/resins\/ion-exchange\/process-characterization-kit-p-11616\"\u003eProcess Characterization Kit Capto MMC ImpRes\u003c\/a\u003e, designed for studying the potential impact that resin ligand density might have on the process outcome.\u003c\/p\u003e\n\n\u003cp\u003eProcess scale purification: prepacked\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"\/shop\/chromatography\/prepacked-columns\/multimodal\/capto-mmc-impres-resin-prepacked-in-readytoprocess-single-use-columns-p-00492\"\u003eReadyToProcess Capto MMC ImpRes columns\u003c\/a\u003e, 1 L and larger columns for clinical manufacturing that minimize the need for cleaning and cleaning validation.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-16468-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-29872-pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"1 L","offer_id":45982347591759,"sku":"17371603","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"5 L","offer_id":45982347624527,"sku":"17371604","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"10 L","offer_id":45982347657295,"sku":"17371605","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"25 mL","offer_id":45982347690063,"sku":"17371601","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL","offer_id":45982347722831,"sku":"17371602","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-4569-original-png_0452a99a-8aac-488d-ab56-dba09d40cf88.png?v=1785960370","url":"https:\/\/www.danyel.co.il\/products\/capto-mmc-impres-multimodal-chromatography-resin-17371603","provider":"danyel biotech","version":"1.0","type":"link"}